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Backbone and side chain resonance assignments of the C-terminal domain of human TGIF1

文献类型：期刊论文

作者Cai, Cong1,3; Nie, Yao1,2; Yue, Xiali3; Zhu, Jiang1; Hu, Rui1; Liu, Maili1; Yang, Yunhuang1
刊名BIOMOLECULAR NMR ASSIGNMENTS
出版日期2019-10-01
卷号13期号:2页码:357-360
ISSN号1874-2718
关键词5 '-TG-3 ' interacting factor-1 Transforming growth-interacting factor 1 Transcription repressor Intrinsically disordered protein Chemical shift assignments
DOI10.1007/s12104-019-09905-x
英文摘要TGIF1 is an essential regulator of cell differentiation in various biological processes, and is associated with holoprosencephaly and many cancers. The C-terminal domain of TGIF1 that was originally defined as repressive domain 2 can interact with a variety of proteins, such as transcription factor Smad2 and co-repressor Sin3A, to mediate the regulative roles of TGIF1 in diverse cell signaling pathways. However, the recognition mechanism of TGIF1 C-terminal domain for different interacting proteins remains unknown. Here, we report the nearly complete H-1, C-13, and N-15 backbone and side chain resonance assignments of TGIF1 C-terminal domain (residues 256-375), laying a foundation for further research on the structure-function relationship of TGIF1.
WOS关键词HOMEODOMAIN PROTEIN TGIF ; INTERACTING FACTOR ; UBIQUITIN LIGASE ; MUTATIONS ; BINDING
资助项目National Natural Science Foundation of China[21575155] ; National Natural Science Foundation of China[21703283]
WOS研究方向Biophysics ; Spectroscopy
语种英语
出版者SPRINGER
WOS记录号WOS:000483690800018
资助机构National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China
源URL[http://ir.wipm.ac.cn/handle/112942/14879]  
专题中国科学院武汉物理与数学研究所
通讯作者Yue, Xiali; Zhu, Jiang
作者单位1.Chinese Acad Sci, State Key Lab Magnet Resonance & Atom Mol Phys, Key Lab Magnet Resonance Biol Syst, Wuhan Inst Phys & Math,Natl Ctr Magnet Resonance, Wuhan 430071, Hubei, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Huazhong Agr Univ, Dept Chem, Coll Sci, Wuhan 430070, Hubei, Peoples R China
推荐引用方式
GB/T 7714		 Cai, Cong,Nie, Yao,Yue, Xiali,et al. Backbone and side chain resonance assignments of the C-terminal domain of human TGIF1[J]. BIOMOLECULAR NMR ASSIGNMENTS,2019,13(2):357-360.
APA Cai, Cong.,Nie, Yao.,Yue, Xiali.,Zhu, Jiang.,Hu, Rui.,...&Yang, Yunhuang.(2019).Backbone and side chain resonance assignments of the C-terminal domain of human TGIF1.BIOMOLECULAR NMR ASSIGNMENTS,13(2),357-360.
MLA Cai, Cong,et al."Backbone and side chain resonance assignments of the C-terminal domain of human TGIF1".BIOMOLECULAR NMR ASSIGNMENTS 13.2(2019):357-360.

入库方式： OAI收割

来源：武汉物理与数学研究所

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