synthesisandmrirelaxationenhancementofmonoexteramidogadoliniumcomplexes
文献类型：期刊论文
| 作者 | Yu KC(俞开潮)1; Wan FX(万福贤)1; Zhang Y(张焱)1; Zhou JL(周锦兰)1; Lu G(卢广)2; Liu ML(刘买利)2; Ding SW(丁尚武)2 |
| 刊名 | chinesejournalofinorganicchemistry
 |
| 出版日期 | 2004 |
| 卷号 | 20期号:4页码:389 |
| ISSN号 | 1001-4861 |
| 英文摘要 | Four new ester-amido ligands were synthesized by esterification of mono-iso-butyl diethylenetriaminepentaacetate and mono-iso-butyl ethylenediaminetetraacetate with N,N'-ethylene bis-lactamide and NN'-1,6-hexamethylenebislactamide, respectively. The corresponding Gd(III) complexes were made by reacting the ligands with Gd2O3. All ligands and complexes were characterized: by FT-IR, H-1 NMR and elemental analysis. The measured longitudinal relaxivity of these complexes were all higher than that of Gd-DTPA. The investigation on cute toxicity and T-1-weighted imaging of complex derived from mono-N,N'-ethylenebislactamide ester diethlenetriaminepentaacetate were performed. No cute toxicity was found. The tested complex exhibited the higher enhancement on MRI signal intensity in rat liver, comparing with Gd-DTPA. |
| 语种 | 英语 |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/17075]  |
| 专题 | 中国科学院武汉物理与数学研究所 |
| 作者单位 | 1.华中科技大学 2.中国科学院武汉物理与数学研究所 |
| 推荐引用方式 GB/T 7714 | Yu KC,Wan FX,Zhang Y,et al. synthesisandmrirelaxationenhancementofmonoexteramidogadoliniumcomplexes[J]. chinesejournalofinorganicchemistry,2004,20(4):389. |
| APA | 俞开潮.,万福贤.,张焱.,周锦兰.,卢广.,...&丁尚武.(2004).synthesisandmrirelaxationenhancementofmonoexteramidogadoliniumcomplexes.chinesejournalofinorganicchemistry,20(4),389. |
| MLA | 俞开潮,et al."synthesisandmrirelaxationenhancementofmonoexteramidogadoliniumcomplexes".chinesejournalofinorganicchemistry 20.4(2004):389. |
入库方式： OAI收割
来源：武汉物理与数学研究所
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