Precisely Tailored DNA Nanostructures and their Theranostic Applications
文献类型：期刊论文
| 作者 | Zhu, B; Wang, LH; Li, J; Fan, CH |
| 刊名 | CHEMICAL RECORD
 |
| 出版日期 | 2017 |
| 卷号 | 17期号:12页码:1213-1230 |
| 关键词 | ROLLING-CIRCLE AMPLIFICATION INTRACELLULAR GENE-REGULATION HYBRIDIZATION CHAIN-REACTIONS SPHERICAL NUCLEIC-ACIDS GOLD NANOPARTICLES IN-VIVO LIVING CELLS DRUG-DELIVERY ORIGAMI NANOSTRUCTURES MESSENGER-RNA |
| ISSN号 | 1527-8999 |
| DOI | 10.1002/tcr.201700019 |
| 文献子类 | 期刊论文 |
| 英文摘要 | A critical challenge in nanotechnology is the limited precision and controllability of the structural parameters, which brings about concerns in uniformity, reproducibility and performance. Self-assembled DNA nanostructures, as a newly emerged type of nano-biomaterials, possess low-nanometer precision, excellent programmability and addressability. They can precisely arrange various molecules and materials to formspatially ordered complex, resulting in unambiguous physical or chemical properties.Because of these, DNA nanostructures have shown great promise in numerous biomedical theranostic applications. In this account, we briefly review the history and advances on construction of DNA nanoarchitectures and superstructures with accurate structural parameters. We focus on recent progress in exploiting these DNA nanostructures as platforms for quantitative biosensing, intracellular diagnosis, imaging, and smart drug delivery. We also discuss key challenges in practical applications. |
| 语种 | 英语 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/31065]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Appl Phys, Div Phys Biol, Shanghai Synchrotron Radiat Facil, Shanghai 201800, Peoples R China 2.Univ Chinese Acad Sci, Beijing 10049, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Appl Phys, Bioimaging Ctr, Shanghai Synchrotron Radiat Facil, Shanghai 201800, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, B,Wang, LH,Li, J,et al. Precisely Tailored DNA Nanostructures and their Theranostic Applications[J]. CHEMICAL RECORD,2017,17(12):1213-1230. |
| APA | Zhu, B,Wang, LH,Li, J,&Fan, CH.(2017).Precisely Tailored DNA Nanostructures and their Theranostic Applications.CHEMICAL RECORD,17(12),1213-1230. |
| MLA | Zhu, B,et al."Precisely Tailored DNA Nanostructures and their Theranostic Applications".CHEMICAL RECORD 17.12(2017):1213-1230. |
入库方式： OAI收割
来源：上海应用物理研究所
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