中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Exploring nanoscale structure change of dermal tissues suffering injury by small angle X-ray scattering and transmission electron microscopy

文献类型:期刊论文

作者Jiang, YZ; Tian, F; Wang, ZY; Niu, YW; Yang, JF; Song, F; Jin, SW; Cao, YM; Dong, JY; Lu, SL
刊名MOLECULAR BIOLOGY REPORTS
出版日期2019
卷号46期号:1页码:67—76
关键词SKIN SCAR THICKNESS COLLAGEN
ISSN号0301-4851
DOI10.1007/s11033-018-4444-9
文献子类期刊论文
英文摘要Scar formation and wound non-healing often occur during wound repair after skin injury, which are still unresolved. Clinic indicated that the structure played an important role in the wound repair. Our previous research showed that the wound over-healed (scar formation) when the integrity and continuity of dermal tissues was destroyed by injury. Other evidences showed that wound healing was impaired in diabetes because the underlying alternation in their skin tissues occurred caused by advanced glycation end products (AGES) aggregation. In order to explore the changes of the structure of skin at nanoscale, the small angle X-ray scattering (SAXS), compared with transmission electron microscopy (TEM), was applied to observe the skin in different pathological status. The results showed that there were some regular patterns in the structure of dermal tissue. The patterns were changed by different pathological status, which would result in wound healing disorder. These will be beneficial for clarifying the pathological mechanisms of wound healing.
语种英语
源URL[http://ir.sinap.ac.cn/handle/331007/31619]  
专题上海应用物理研究所_中科院上海应用物理研究所2011-2017年
作者单位1.Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Dept Burns & Plast Surg, Shanghai 200025, Peoples R China
2.Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Shanghai Burns Inst, Shanghai 200025, Peoples R China;
3.Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai Synchrotron Radiat Facil, Shanghai 201204, Peoples R China;
4.Shanghai Univ Tradit Chinese Med, Shanghai Tradit Chinese Med Integrated Hosp, Shanghai 200082, Peoples R China;
推荐引用方式
GB/T 7714
Jiang, YZ,Tian, F,Wang, ZY,et al. Exploring nanoscale structure change of dermal tissues suffering injury by small angle X-ray scattering and transmission electron microscopy[J]. MOLECULAR BIOLOGY REPORTS,2019,46(1):67—76.
APA Jiang, YZ.,Tian, F.,Wang, ZY.,Niu, YW.,Yang, JF.,...&Lu, SL.(2019).Exploring nanoscale structure change of dermal tissues suffering injury by small angle X-ray scattering and transmission electron microscopy.MOLECULAR BIOLOGY REPORTS,46(1),67—76.
MLA Jiang, YZ,et al."Exploring nanoscale structure change of dermal tissues suffering injury by small angle X-ray scattering and transmission electron microscopy".MOLECULAR BIOLOGY REPORTS 46.1(2019):67—76.

入库方式: OAI收割

来源:上海应用物理研究所

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