Exploring nanoscale structure change of dermal tissues suffering injury by small angle X-ray scattering and transmission electron microscopy
文献类型：期刊论文
| 作者 | Jiang, YZ; Tian, F; Wang, ZY; Niu, YW; Yang, JF; Song, F; Jin, SW; Cao, YM; Dong, JY; Lu, SL |
| 刊名 | MOLECULAR BIOLOGY REPORTS
 |
| 出版日期 | 2019 |
| 卷号 | 46期号:1页码:67—76 |
| 关键词 | SKIN SCAR THICKNESS COLLAGEN |
| ISSN号 | 0301-4851 |
| DOI | 10.1007/s11033-018-4444-9 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Scar formation and wound non-healing often occur during wound repair after skin injury, which are still unresolved. Clinic indicated that the structure played an important role in the wound repair. Our previous research showed that the wound over-healed (scar formation) when the integrity and continuity of dermal tissues was destroyed by injury. Other evidences showed that wound healing was impaired in diabetes because the underlying alternation in their skin tissues occurred caused by advanced glycation end products (AGES) aggregation. In order to explore the changes of the structure of skin at nanoscale, the small angle X-ray scattering (SAXS), compared with transmission electron microscopy (TEM), was applied to observe the skin in different pathological status. The results showed that there were some regular patterns in the structure of dermal tissue. The patterns were changed by different pathological status, which would result in wound healing disorder. These will be beneficial for clarifying the pathological mechanisms of wound healing. |
| 语种 | 英语 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/31619]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 作者单位 | 1.Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Dept Burns & Plast Surg, Shanghai 200025, Peoples R China 2.Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Shanghai Burns Inst, Shanghai 200025, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai Synchrotron Radiat Facil, Shanghai 201204, Peoples R China; 4.Shanghai Univ Tradit Chinese Med, Shanghai Tradit Chinese Med Integrated Hosp, Shanghai 200082, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Jiang, YZ,Tian, F,Wang, ZY,et al. Exploring nanoscale structure change of dermal tissues suffering injury by small angle X-ray scattering and transmission electron microscopy[J]. MOLECULAR BIOLOGY REPORTS,2019,46(1):67—76. |
| APA | Jiang, YZ.,Tian, F.,Wang, ZY.,Niu, YW.,Yang, JF.,...&Lu, SL.(2019).Exploring nanoscale structure change of dermal tissues suffering injury by small angle X-ray scattering and transmission electron microscopy.MOLECULAR BIOLOGY REPORTS,46(1),67—76. |
| MLA | Jiang, YZ,et al."Exploring nanoscale structure change of dermal tissues suffering injury by small angle X-ray scattering and transmission electron microscopy".MOLECULAR BIOLOGY REPORTS 46.1(2019):67—76. |
入库方式： OAI收割
来源：上海应用物理研究所
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