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Does Depressive-Type Schizophrenia Exist? How Do We Prove It? An Updated Review and Overview

文献类型：期刊论文

作者Huang, Jianjie1; Zhuo, Chuanjun1,2,3,4,5; Song, Xueqin6; Li, Yachen3,4,5; Jing, Rixing7; Tian, Hongjun3,4,5; Wang, Lina3,4,5; Mao, Fuqiang5; Li, Shen5; Jiang, Ronghuan8
刊名JOURNAL OF NERVOUS AND MENTAL DISEASE
出版日期2019-07-01
卷号207期号:7页码:555-560
关键词Depressive-type schizophrenia magnetic resonance imaging genetics deep learning classifier
ISSN号0022-3018
DOI10.1097/NMD.0000000000001004
通讯作者Zhuo, Chuanjun(chuanjunzhuotjmh@163.com) ; Jiang, Ronghuan(jiangrh55@126.com) ; Chen, Suling(csl0577zxh@163.com)
英文摘要Depressive symptoms can occur at any point in the duration of schizophrenia. However, we are unable to predict if or when depression will occur in schizophrenic patients. Simultaneously, the standard treatment of depression in schizophrenic patients is the combination of antidepressants and antipsychotics, which has been minimally effective for most patients. Based on several studies, we hypothesized the existence of depressive-type schizophrenia and reviewed the substantial evidence supporting the hypothesis of depressive-type schizophrenia. Simultaneously, we propose technical methods to explore the neuropathology of depressive-type schizophrenia in order to identify the disease during its early stages and to predict how patients will respond to the standard treatment strategies. We believe that the new classification of depressive-type schizophrenia will differentiate it from other forms of depression. In return, this will aid in the discovery of new therapeutic strategies for combatting this disease.
WOS关键词PREFRONTAL CORTEX ; SYMPTOMS ; DISORDER ; ANTIDEPRESSANTS ; ANTIPSYCHOTICS ; PSYCHOSIS ; ANXIETY
资助项目Tianjin Health Bureau Foundation[2014KR02] ; National Natural Science Foundation of China[81871052] ; Key Projects of the Natural Science Foundation of Tianjin, China[17JCZDJC35700] ; Wenzhou Science and Technology Project[ZS2017011]
WOS研究方向Neurosciences & Neurology ; Psychiatry
语种英语
WOS记录号WOS:000475374300004
出版者LIPPINCOTT WILLIAMS & WILKINS
资助机构Tianjin Health Bureau Foundation ; National Natural Science Foundation of China ; Key Projects of the Natural Science Foundation of Tianjin, China ; Wenzhou Science and Technology Project
源URL[http://ir.ia.ac.cn/handle/173211/26888]  
专题自动化研究所_模式识别国家重点实验室
通讯作者Zhuo, Chuanjun; Jiang, Ronghuan; Chen, Suling
作者单位1.Wenzhou Seventh Peoples Hosp, Dept Psychiat, 522 Xioshandong Rd, Wenzhou 325000, Peoples R China
2.Jining Med Univ, Dept Psychiat, Jining, Peoples R China
3.Tianjin Anding Hosp, Tianjin Mental Hlth Ctr, Dept Psychiatr Neuroimaging Genet Lab & Comorbid, Tianjin, Peoples R China
4.Tianjin Med Univ, Mental Hlth Teaching Hosp, Tianjin, Peoples R China
5.Tianjin Med Univ, Dept Psychiat, Tianjin, Peoples R China
6.Zhengzhou Univ, Affiliated Hosp 1, Dept Psychiat, Zhengzhou, Henan, Peoples R China
7.Chinese Acad Sci, Inst Automat, China Natl Key Lab, Dept Pattern Recognit, Beijing, Peoples R China
8.Chinese Peoples Liberat Army, Gen Hosp, Hosp 301, Dept Psychosomat Med, Beijing, Peoples R China
推荐引用方式
GB/T 7714		 Huang, Jianjie,Zhuo, Chuanjun,Song, Xueqin,et al. Does Depressive-Type Schizophrenia Exist? How Do We Prove It? An Updated Review and Overview[J]. JOURNAL OF NERVOUS AND MENTAL DISEASE,2019,207(7):555-560.
APA Huang, Jianjie.,Zhuo, Chuanjun.,Song, Xueqin.,Li, Yachen.,Jing, Rixing.,...&Chen, Suling.(2019).Does Depressive-Type Schizophrenia Exist? How Do We Prove It? An Updated Review and Overview.JOURNAL OF NERVOUS AND MENTAL DISEASE,207(7),555-560.
MLA Huang, Jianjie,et al."Does Depressive-Type Schizophrenia Exist? How Do We Prove It? An Updated Review and Overview".JOURNAL OF NERVOUS AND MENTAL DISEASE 207.7(2019):555-560.

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来源：自动化研究所

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