Residual cancerous lesion and vein tumour thrombus identified intraoperatively using a fluorescence navigation system in liver surgery
文献类型：期刊论文
| 作者 | He, Pan1,2; Su, Song1; Fang, Cheng1; He, Kai1; Chi, Chongwei3,4 ; Xia, Xianming1; Tian, Jie3; Li, Bo1
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| 刊名 | ANZ JOURNAL OF SURGERY
 |
| 出版日期 | 2019-07-01 |
| 卷号 | 89期号:7-8页码:E308-E314 |
| 关键词 | hepatectomy hepatocellular carcinoma liver near infrared |
| ISSN号 | 1445-1433 |
| DOI | 10.1111/ans.15282 |
| 通讯作者 | Li, Bo(liboer2002@126.com) |
| 英文摘要 | Aim The main aims of this study are to investigate the clinical application value of using indocyanine green fluorescence imaging for ensuring complete resection of tumour tissue during hepatectomy and to evaluate the diagnostic efficacy of near-infrared (NIR) fluorescence imaging system using indocyanine green in hepatectomy. Methods After undergoing liver resection at the Affiliated Hospital of Southwest Medical University from July 2017 to May 2018, 35 eligible patients were included in this study. The liver surface and resection margin were intraoperatively assessed by intraoperative ultrasonography and NIR fluorescence imaging, after intravenous administration of indocyanine green (0.5 mg/kg) 72-96 h prior to surgery. The intraoperative observations were compared with the pathological findings in the liver. Results In the 35 patients, a total of 53 lesions were found, of which 42 were malignant lesions. The analysis results showed that the sensitivity and accuracy of detection using NIR fluorescence imaging were significantly higher than with intraoperative ultrasonography (P < 0.05). However, there was no difference between contrast-enhanced helical computed tomography and NIR fluorescence imaging in finding lesions (P > 0.05). In addition, 11 new suspicious lesions were detected only by NIR fluorescence imaging in the liver surface and resection margin during surgery, four of which were hepatocellular carcinoma. We also detected four vein tumour thrombi using the NIR fluorescence navigation system. Conclusions The NIR fluorescence navigation system enables the identification of small tumours, residual cancer tissues in resection margin and venous tumour embolies in real time and enhances the accuracy and integrity of liver resection. |
| WOS关键词 | EARLY HEPATOCELLULAR-CARCINOMA ; INDOCYANINE GREEN ; GUIDED SURGERY ; RESECTION ; TRANSPLANTATION |
| WOS研究方向 | Surgery |
| 语种 | 英语 |
| WOS记录号 | WOS:000478741700005 |
| 出版者 | WILEY |
| 源URL | [http://ir.ia.ac.cn/handle/173211/27520]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 通讯作者 | Li, Bo |
| 作者单位 | 1.Southwest Med Univ, Affiliated Hosp, Dept Hepatobiliary Surg, Luzhou 646000, Peoples R China 2.Southwest Med Univ, Affiliated Hosp, Dept Anesthesiol, Luzhou, Peoples R China 3.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging, Beijing, Peoples R China 4.Beijing Digital Precis Med Technol Co Ltd, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Pan,Su, Song,Fang, Cheng,et al. Residual cancerous lesion and vein tumour thrombus identified intraoperatively using a fluorescence navigation system in liver surgery[J]. ANZ JOURNAL OF SURGERY,2019,89(7-8):E308-E314. |
| APA | He, Pan.,Su, Song.,Fang, Cheng.,He, Kai.,Chi, Chongwei.,...&Li, Bo.(2019).Residual cancerous lesion and vein tumour thrombus identified intraoperatively using a fluorescence navigation system in liver surgery.ANZ JOURNAL OF SURGERY,89(7-8),E308-E314. |
| MLA | He, Pan,et al."Residual cancerous lesion and vein tumour thrombus identified intraoperatively using a fluorescence navigation system in liver surgery".ANZ JOURNAL OF SURGERY 89.7-8(2019):E308-E314. |
入库方式： OAI收割
来源：自动化研究所
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