中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Significance of Resveratrol in Clinical Management of Chronic Diseases

文献类型:期刊论文

作者Wahab, Awais3; Gao, Kuo3; Jia, Caixia3; Zhang, Feilong3; Tian, Guihua1,3; Murtaza, Ghulam2,3,4; Chen, Jianxin3
刊名MOLECULES
出版日期2017-08-01
卷号22期号:8页码:19
关键词pre-clinical studies clinical studies absorption toxicity diabetes mellitus obesity cardiovascular diseases cancer aging
ISSN号1420-3049
DOI10.3390/molecules22081329
通讯作者Murtaza, Ghulam(gmdogar356@gmail.com) ; Chen, Jianxin(cjx@bucm.edu.cn)
英文摘要Resveratrol could be beneficial to health and provides protection against a wide array of pathologies and age-associated problems, as evident from preclinical studies. However, a comparison of animal and human studies reveals that this dietary polyphenol cannot protect against metabolic diseases and their associated complications. The clinical outcomes are affected by many factors such as sample size. This article not only presents a comprehensive review of the current advances concerning the dose, the extent of absorption, interaction and toxicity of resveratrol in human studies, but also describes its therapeutic effects against several chronic diseases such as diabetes mellitus, obesity, cardiovascular diseases, cancer and aging and the related diseases.
WOS关键词CORONARY-ARTERY-DISEASE ; GENETICALLY HETEROGENEOUS MICE ; RANDOMIZED CONTROLLED-TRIALS ; TYPE-2 DIABETES-MELLITUS ; BLOOD MONONUCLEAR-CELLS ; TRANS-RESVERATROL ; PRIMARY PREVENTION ; LIFE-SPAN ; IN-VITRO ; ALZHEIMERS-DISEASE
资助项目National Natural Science Foundation of China[81403468] ; National Natural Science Foundation of China[81674050] ; National Natural Science Foundation of China[81522051] ; Beijing Nova Program[xx2014B049] ; Beijing Nova Program[xx2013032]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000408602900093
出版者MDPI AG
资助机构National Natural Science Foundation of China ; Beijing Nova Program
源URL[http://ir.ia.ac.cn/handle/173211/28030]  
专题离退休人员
通讯作者Murtaza, Ghulam; Chen, Jianxin
作者单位1.Beijing Univ Chinese Med, Dongzhimen Hosp, Beijing 100700, Peoples R China
2.COMSATS, Inst Informat Technol, Dept Pharm, Abbottabad 22060, Pakistan
3.Beijing Univ Chinese Med, Sch Preclin Med, Beijing 100029, Peoples R China
4.Chinese Acad Sci, Inst Automat, Beijing 100029, Peoples R China
推荐引用方式
GB/T 7714
Wahab, Awais,Gao, Kuo,Jia, Caixia,et al. Significance of Resveratrol in Clinical Management of Chronic Diseases[J]. MOLECULES,2017,22(8):19.
APA Wahab, Awais.,Gao, Kuo.,Jia, Caixia.,Zhang, Feilong.,Tian, Guihua.,...&Chen, Jianxin.(2017).Significance of Resveratrol in Clinical Management of Chronic Diseases.MOLECULES,22(8),19.
MLA Wahab, Awais,et al."Significance of Resveratrol in Clinical Management of Chronic Diseases".MOLECULES 22.8(2017):19.

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