Chemical constituents, and pharmacological and toxicological effects of Cynomorium songaricum: An overview
文献类型：期刊论文
| 作者 | Cheng, Dan3; Zheng, Junchao3; Ma, Suya3; Murtaza, Ghulam1,2,3; Wahab, Awais3; Yu, Changying3; Liu, Jingwei3; Lu, Yi3
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| 刊名 | TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
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| 出版日期 | 2017-11-01 |
| 卷号 | 16期号:11页码:2689-2696 |
| 关键词 | Cynomorium Chemical constituents Inflammation Aging Fatigue Virus Tumor Toxicological effect |
| ISSN号 | 1596-5996 |
| DOI | 10.4314/tjpr.v16i11.17 |
| 通讯作者 | Lu, Yi(yilubucm@gmail.com) |
| 英文摘要 | Purpose: To review the chemical constituents, and the pharmacological and toxicological effects of Cynomorium songaricum (C. songaricum) and explore its potentials for further development as an alternative medicine. Methods: A large number of research articles related to "Cynomorium songaricum" "pharmacological effects", "toxicological effects" and "chemical composition" in English and Chinese language were retrieved through an extensive literature review using various electronic databases including Medline (1966 - 2017) and EMBASE (1980 - 2017). Results: Ethyl acetate and aqueous extracts of C. songaricum have promising pharmacological activities, due to the presence of various flavonoids, triterpenes and polysaccharides. In addition to promising effects against inflammation, aging, fatigue, viruses and cancer, C. songaricum has a protective effect on the nervous system and regulates hormones and immune functions. Oxidative regulation of hormone levels has a certain correlation with its pharmacological activities, e.g., cognitive functions, but its mechanism is not yet known, indicating the need for further research. Toxicity studies on C. songaricum have shown that it is not genotoxic to animals, but further toxicological studies are required to ascertain its safety in clinical use. Conclusion: C. songaricum is a biologically important plant which has many proven bioactivities; however, it requires further studies to determine the mechanistic aspects of its pharmacological effects. |
| 资助项目 | New Century Excellent Talents of China[NECT-13-0695] ; National Nature Science Foundation of China[81102623] ; Beijing Nova Program[xx2013032] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000418472200017 |
| 出版者 | PHARMACOTHERAPY GROUP |
| 资助机构 | New Century Excellent Talents of China ; National Nature Science Foundation of China ; Beijing Nova Program |
| 源URL | [http://ir.ia.ac.cn/handle/173211/28229]  |
| 专题 | 离退休人员 |
| 通讯作者 | Lu, Yi |
| 作者单位 | 1.Chinese Acad Sci, Inst Automat, Beijing, Peoples R China 2.COMSATS Inst Informat Technol Abbottabad, Dept Pharm, Abbottabad, Pakistan 3.Beijing Univ Chinese Med, Sch Preclin Med, Beijing 100029, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cheng, Dan,Zheng, Junchao,Ma, Suya,et al. Chemical constituents, and pharmacological and toxicological effects of Cynomorium songaricum: An overview[J]. TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH,2017,16(11):2689-2696. |
| APA | Cheng, Dan.,Zheng, Junchao.,Ma, Suya.,Murtaza, Ghulam.,Wahab, Awais.,...&Lu, Yi.(2017).Chemical constituents, and pharmacological and toxicological effects of Cynomorium songaricum: An overview.TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH,16(11),2689-2696. |
| MLA | Cheng, Dan,et al."Chemical constituents, and pharmacological and toxicological effects of Cynomorium songaricum: An overview".TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH 16.11(2017):2689-2696. |
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来源：自动化研究所
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