Silicene: Wet-Chemical Exfoliation Synthesis and Biodegradable Tumor Nanomedicine
文献类型：期刊论文
| 作者 | Lin, Han; Qiu, Wujie; Liu, Jianjun; Yu, Luodan; Gao, Shanshan; Yao, Heliang; Chen, Yu; Shi, Jianlin |
| 刊名 | ADVANCED MATERIALS
 |
| 出版日期 | 2019-09-01 |
| 卷号 | 31期号:37 |
| ISSN号 | 0935-9648 |
| 关键词 | 2D topology biodegradation nanomedicine silicene wet-chemical exfoliation |
| DOI | 10.1002/adma.201903013 |
| 文献子类 | Article |
| 英文摘要 | Silicon-based biomaterials play an indispensable role in biomedical engineering; however, due to the lack of intrinsic functionalities of silicon, the applications of silicon-based nanomaterials are largely limited to only serving as carriers for drug delivery systems. Meanwhile, the intrinsically poor biodegradation nature for silicon-based biomaterials as typical inorganic materials also impedes their further in vivo biomedical use and clinical translation. Herein, by the rational design and wet chemical exfoliation synthesis of the 2D silicene nanosheets, traditional 0D nanoparticulate nanosystems are transformed into 2D material systems, silicene nanosheets (SNSs), which feature an intriguing physiochemical nature for photo-triggered therapeutics and diagnostic imaging and greatly favorable biological effects of biocompatibility and biodegradation. In combination with DFT-based molecular dynamics (MD) calculations, the underlying mechanism of silicene interactions with bio-milieu and its degradation behavior are probed under specific simulated physiological conditions. This work introduces a new form of silicon-based biomaterials with 2D structure featuring biodegradability, biocompatibility, and multifunctionality for theranostic nanomedicine, which is expected to promise high clinical potentials. |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.sic.ac.cn/handle/331005/26867]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 推荐引用方式 GB/T 7714 | Lin, Han,Qiu, Wujie,Liu, Jianjun,et al. Silicene: Wet-Chemical Exfoliation Synthesis and Biodegradable Tumor Nanomedicine[J]. ADVANCED MATERIALS,2019,31(37). |
| APA | Lin, Han.,Qiu, Wujie.,Liu, Jianjun.,Yu, Luodan.,Gao, Shanshan.,...&Shi, Jianlin.(2019).Silicene: Wet-Chemical Exfoliation Synthesis and Biodegradable Tumor Nanomedicine.ADVANCED MATERIALS,31(37). |
| MLA | Lin, Han,et al."Silicene: Wet-Chemical Exfoliation Synthesis and Biodegradable Tumor Nanomedicine".ADVANCED MATERIALS 31.37(2019). |
入库方式： OAI收割
来源：上海硅酸盐研究所
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