A hydrogenated black TiO2 coating with excellent effects for photothermal therapy of bone tumor and bone regeneration
文献类型:期刊论文
作者 | Zhang, Wenxin; Gu, Jingping; Li, Kai; Zhao, Jun; Ma, Hongshi; Wu, Chengtie; Zhang, Cheng; Xie, Youtao; Yang, Fei; Zheng, Xuebin |
刊名 | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
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出版日期 | 2019-09-01 |
卷号 | 102页码:458 |
关键词 | Titania Photothermal therapy Micro/nano-structure Ti-OH groups Bone tumor |
ISSN号 | 0928-4931 |
DOI | 10.1016/j.msec.2019.04.025 |
文献子类 | Article |
英文摘要 | The clinical treatment of bone tumors usually brings about residual tumor cells and large bone defects after tumor removal surgery. To solve this problem, it is imperative to develop a novel implant with bi-functions for eliminating the residual tumor cells and repairing bone defects. In this study, hydrogenated black TiO2 (H-TiO2) coating with hierarchical micro/nano-topographies is fabricated by induction suspension plasma spraying (ISPS). The fabricated H-TiO2 coating possessed excellent and controllable photothermal effect in inhibiting the tumor growth under 808 nm NIR laser irradiation in vitro and in vivo. The hierarchical hybrid micro/nano-structured surface and Ti-OH groups improved the adhesion, proliferation, differentiation and osteogenic gene expressions of rat bone mesenchymal stem cells (rBMSCs). These results demonstrate that the H-TiO2 coating may be a promising implant material for the treatment of bone tumors and bone regeneration. |
WOS研究方向 | Materials Science |
语种 | 英语 |
出版者 | ELSEVIER SCIENCE BV |
源URL | [http://ir.sic.ac.cn/handle/331005/26883] ![]() |
专题 | 中国科学院上海硅酸盐研究所 |
推荐引用方式 GB/T 7714 | Zhang, Wenxin,Gu, Jingping,Li, Kai,et al. A hydrogenated black TiO2 coating with excellent effects for photothermal therapy of bone tumor and bone regeneration[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2019,102:458. |
APA | Zhang, Wenxin.,Gu, Jingping.,Li, Kai.,Zhao, Jun.,Ma, Hongshi.,...&Zheng, Xuebin.(2019).A hydrogenated black TiO2 coating with excellent effects for photothermal therapy of bone tumor and bone regeneration.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,102,458. |
MLA | Zhang, Wenxin,et al."A hydrogenated black TiO2 coating with excellent effects for photothermal therapy of bone tumor and bone regeneration".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 102(2019):458. |
入库方式: OAI收割
来源:上海硅酸盐研究所
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