Sr- and Si-containing bioceramic stimulate in vitro osteogenesis
文献类型：期刊论文
| 作者 | Lin, Chucheng; Zhu, Huiying; Zeng, Yi |
| 刊名 | SURFACE & COATINGS TECHNOLOGY
 |
| 出版日期 | 2019-05-15 |
| 卷号 | 365页码:129 |
| 关键词 | Sr-5(PO4)(2)SiO4 bioceramic Cytocompatibility Gene expression Osteogenesis |
| ISSN号 | 0257-8972 |
| DOI | 10.1016/j.surfcoat.2018.10.063 |
| 文献子类 | Article; Proceedings Paper |
| 英文摘要 | To develop composite bioactive bioceramics for bone tissue engineering, Sr-5(PO4)(2)SiO4 (SrPS) bioceramics that containing bioactive Si and Sr ions were successfully prepared by compression molding in the present study. Cell proliferation and molecular biology actions were studied using the rabbit bone marrow stromal cells (rBMSCs) to evaluate the biological properties of this novel bioceramic. The results showed that comparing with traditional beta-tricalcium phosphate (beta-TCP), the prepared SrPS bioceramics presented satisfied cytocompatibility and enhanced cell proliferation. In addition, the expression of the bone-related gene bone morphorgenetic protein 2 (BMP2) and osteocalcin (OCN) of rBMSCs was also improved. These results demonstrated that the prepared SrPS bioceramics could stimulate osteogenic in vitro, demonstrating that they might have bright potential for being used as bone repair material. |
| WOS研究方向 | Materials Science ; Physics |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCIENCE SA |
| 源URL | [http://ir.sic.ac.cn/handle/331005/27113]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 推荐引用方式 GB/T 7714 | Lin, Chucheng,Zhu, Huiying,Zeng, Yi. Sr- and Si-containing bioceramic stimulate in vitro osteogenesis[J]. SURFACE & COATINGS TECHNOLOGY,2019,365:129. |
| APA | Lin, Chucheng,Zhu, Huiying,&Zeng, Yi.(2019).Sr- and Si-containing bioceramic stimulate in vitro osteogenesis.SURFACE & COATINGS TECHNOLOGY,365,129. |
| MLA | Lin, Chucheng,et al."Sr- and Si-containing bioceramic stimulate in vitro osteogenesis".SURFACE & COATINGS TECHNOLOGY 365(2019):129. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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