Ultrathin Molybdenum Carbide MXene with Fast Biodegradability for Highly Efficient Theory-Oriented Photonic Tumor Hyperthermia
文献类型：期刊论文
| 作者 | Feng, Wei; Wang, Rongyan; Zhou, Yadan; Ding, Li; Gao, Xiang; Zhou, Bangguo; Hu, Ping; Chen, Yu |
| 刊名 | ADVANCED FUNCTIONAL MATERIALS
 |
| 出版日期 | 2019-05-01 |
| 卷号 | 29期号:22 |
| 关键词 | biodegradability cancer therapy Mo2C MXene nanomedicine photothermal conversion |
| ISSN号 | 1616-301X |
| DOI | 10.1002/adfm.201901942 |
| 文献子类 | Article |
| 英文摘要 | The explosion of emerging high-performance 2D MXenes in theranostic nanomedicine is still at the preliminary stage. Despite tremendous efforts devoted to photonic tumor hyperthermia, current photothermal-conversion nanoagents still suffer from critical issues preventing further clinical translation such as low biodegradability. Here, for the first time, the construction of novel 2D molybdenum carbide (Mo2C) MXenes for photonic tumor hyperthermia is reported. The structure of both bulk Mo2Ga2C ceramic and Mo2C MXene is fully revealed. Especially, computational simulation, as a novel strategy and a powerful tool for photonic-performance prediction, is employed to reveal that Mo2C MXene is featured with intense near-infrared (NIR) absorption, covering the first and the second biological transparency window (NIR I and II). After further surface engineering with polyvinyl alcohol (PVA), Mo2C-PVA nanoflakes exhibit high biocompatibility and fast degradability. Importantly, it is experimentally corroborated that Mo2C-PVA nanoflakes possess intriguing broad absorption band spanning NIR in both the I and II regions, and desirable photothermal-conversion efficiency (24.5% for NIR I and 43.3% for NIR II). This study not only broadens the nanomedical applications of MXene by fabricating novel material members (Mo2C), but also provides the paradigm of inorganic multifunctional biomedical nanoplatform with desirable biodegradability and high therapeutic performance. |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.sic.ac.cn/handle/331005/27130]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 推荐引用方式 GB/T 7714 | Feng, Wei,Wang, Rongyan,Zhou, Yadan,et al. Ultrathin Molybdenum Carbide MXene with Fast Biodegradability for Highly Efficient Theory-Oriented Photonic Tumor Hyperthermia[J]. ADVANCED FUNCTIONAL MATERIALS,2019,29(22). |
| APA | Feng, Wei.,Wang, Rongyan.,Zhou, Yadan.,Ding, Li.,Gao, Xiang.,...&Chen, Yu.(2019).Ultrathin Molybdenum Carbide MXene with Fast Biodegradability for Highly Efficient Theory-Oriented Photonic Tumor Hyperthermia.ADVANCED FUNCTIONAL MATERIALS,29(22). |
| MLA | Feng, Wei,et al."Ultrathin Molybdenum Carbide MXene with Fast Biodegradability for Highly Efficient Theory-Oriented Photonic Tumor Hyperthermia".ADVANCED FUNCTIONAL MATERIALS 29.22(2019). |
入库方式： OAI收割
来源：上海硅酸盐研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。