CT/MRI-Guided Synergistic Radiotherapy and X-ray Inducible Photodynamic Therapy Using Tb-Doped Gd-W-Nanoscintillators
文献类型：期刊论文
| 作者 | Yu, Xujiang; Liu, Xinyi; Wu, Weijie; Yang, Kai; Mao, Rihua; Ahmad, Farooq; Chen, Xiaoyuan; Li, Wanwan |
| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2019-02-11 |
| 卷号 | 58期号:7页码:2017 |
| 关键词 | computed tomography magnetic resonance imaging nanoscintillators radiotherapy X-ray inducible photodynamic therapy |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.201812272 |
| 文献子类 | Article |
| 英文摘要 | The use of X-rays instead of UV/Vis light to trigger photodynamic therapy, named X-ray inducible photodynamic therapy, holds tremendous promise due to a high penetration capacity in tissues and is worthy of in-depth study. In this study, a novel multifunctional nanoagent based on Merocyanine 540-coupled Gd-2(WO4)(3):Tb nanoscintillators and the vitalization of its abilities for dual-modal computed tomography and the magnetic-resonance-imaging-guided synergistic radio-/X-ray inducible photodynamic therapy of tumors is reported. Synergistic therapies show a higher tumor growth inhibition efficiency at a lower X-ray dose than radiotherapy alone. Through this proof-of-concept work, a way to tactfully understand and utilize nanoscintillators for cancer theranostics is shown. |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.sic.ac.cn/handle/331005/27336]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 推荐引用方式 GB/T 7714 | Yu, Xujiang,Liu, Xinyi,Wu, Weijie,et al. CT/MRI-Guided Synergistic Radiotherapy and X-ray Inducible Photodynamic Therapy Using Tb-Doped Gd-W-Nanoscintillators[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2019,58(7):2017. |
| APA | Yu, Xujiang.,Liu, Xinyi.,Wu, Weijie.,Yang, Kai.,Mao, Rihua.,...&Li, Wanwan.(2019).CT/MRI-Guided Synergistic Radiotherapy and X-ray Inducible Photodynamic Therapy Using Tb-Doped Gd-W-Nanoscintillators.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,58(7),2017. |
| MLA | Yu, Xujiang,et al."CT/MRI-Guided Synergistic Radiotherapy and X-ray Inducible Photodynamic Therapy Using Tb-Doped Gd-W-Nanoscintillators".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 58.7(2019):2017. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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