Upconversion-based photodynamic cancer therapy
文献类型：期刊论文
| 作者 | Liu, Yanyan; Meng, Xianfu; Bu, Wenbo |
| 刊名 | COORDINATION CHEMISTRY REVIEWS
 |
| 出版日期 | 2019-01-15 |
| 卷号 | 379页码:82 |
| 关键词 | Photodynamic therapy Upconversion nanoparticles Photosensitizers UCNP-based PDT Synergistic therapy |
| ISSN号 | 0010-8545 |
| DOI | 10.1016/j.ccr.2017.09.006 |
| 文献子类 | Review |
| 英文摘要 | Photodynamic therapy (PDT) has become widely accepted and utilized for tumor therapy. Considering the natural shortcomings (e.g., lack of an ideal photosensitizer and limited light penetration depth), lanthanide doped upconversion nanoparticles (Ln-doped UCNP), which can be excited with near-infrared light (NIR) for UV/visible/NIR upconversion luminescence (UCL) emissions, show great potential for augmenting biological treatment with PDT for solid tumors and for visual bioimaging of disease lesions. This review summarizes the basic concepts and important influence factors on PDT, the optimized construction of UCNP-based photosensitizer (UCNP-PS) systems, and some representative examples of UCNP-based PDT (UCPDT) applications in combination with other traditional therapy methods, such as chemotherapy, radiotherapy, photothermal therapy (PIT) and gene therapy. This review will provide guidance for the design and fabrication of future new UCNP-based nanocomposites for synergistic UC-PDT therapy. (C) 2017 Elsevier B.V. All rights reserved. |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCIENCE SA |
| 源URL | [http://ir.sic.ac.cn/handle/331005/27396]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 推荐引用方式 GB/T 7714 | Liu, Yanyan,Meng, Xianfu,Bu, Wenbo. Upconversion-based photodynamic cancer therapy[J]. COORDINATION CHEMISTRY REVIEWS,2019,379:82. |
| APA | Liu, Yanyan,Meng, Xianfu,&Bu, Wenbo.(2019).Upconversion-based photodynamic cancer therapy.COORDINATION CHEMISTRY REVIEWS,379,82. |
| MLA | Liu, Yanyan,et al."Upconversion-based photodynamic cancer therapy".COORDINATION CHEMISTRY REVIEWS 379(2019):82. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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