中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Upconversion-based photodynamic cancer therapy

文献类型:期刊论文

作者Liu, Yanyan; Meng, Xianfu; Bu, Wenbo
刊名COORDINATION CHEMISTRY REVIEWS
出版日期2019-01-15
卷号379页码:82
ISSN号0010-8545
关键词Photodynamic therapy Upconversion nanoparticles Photosensitizers UCNP-based PDT Synergistic therapy
DOI10.1016/j.ccr.2017.09.006
文献子类Review
英文摘要Photodynamic therapy (PDT) has become widely accepted and utilized for tumor therapy. Considering the natural shortcomings (e.g., lack of an ideal photosensitizer and limited light penetration depth), lanthanide doped upconversion nanoparticles (Ln-doped UCNP), which can be excited with near-infrared light (NIR) for UV/visible/NIR upconversion luminescence (UCL) emissions, show great potential for augmenting biological treatment with PDT for solid tumors and for visual bioimaging of disease lesions. This review summarizes the basic concepts and important influence factors on PDT, the optimized construction of UCNP-based photosensitizer (UCNP-PS) systems, and some representative examples of UCNP-based PDT (UCPDT) applications in combination with other traditional therapy methods, such as chemotherapy, radiotherapy, photothermal therapy (PIT) and gene therapy. This review will provide guidance for the design and fabrication of future new UCNP-based nanocomposites for synergistic UC-PDT therapy. (C) 2017 Elsevier B.V. All rights reserved.
WOS研究方向Chemistry
语种英语
出版者ELSEVIER SCIENCE SA
源URL[http://ir.sic.ac.cn/handle/331005/27396]  
专题中国科学院上海硅酸盐研究所
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Liu, Yanyan,Meng, Xianfu,Bu, Wenbo. Upconversion-based photodynamic cancer therapy[J]. COORDINATION CHEMISTRY REVIEWS,2019,379:82.
APA Liu, Yanyan,Meng, Xianfu,&Bu, Wenbo.(2019).Upconversion-based photodynamic cancer therapy.COORDINATION CHEMISTRY REVIEWS,379,82.
MLA Liu, Yanyan,et al."Upconversion-based photodynamic cancer therapy".COORDINATION CHEMISTRY REVIEWS 379(2019):82.

入库方式: OAI收割

来源:上海硅酸盐研究所

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