中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Antibacterial ability, cytocompatibility and hemocompatibility of fluorinated graphene

文献类型:期刊论文

作者Geng, Hao; Wang, Tianbo; Cao, Huiliang; Zhu, Hongqin; Di, Zengfeng; Liu, Xuanyong
刊名COLLOIDS AND SURFACES B-BIOINTERFACES
出版日期2019
卷号173页码:681
关键词Fluorinated graphene Plasma modification Antibacterial property Biological response
ISSN号0927-7765
DOI10.1016/j.colsurfb.2018.10.050
文献子类Article
英文摘要Graphene halides are promising two-dimensional systems which have interesting physical and chemical properties. In particular, high quality fluorinated graphene offers a great potential in modulating variable properties by regulating its surface microstructure. Moreover, the fluorine introduction and carbon-fluorine bonding characters will enable some interesting biological response. Here, the biological responses to bacteria and cells of fluorinated graphene were studied. Present work revealed that partially fluorinated graphene behaved satisfactory antibacterial ability. Fluorinated graphene showed well facilitating function to cell adhesion in early period, however, after a longer incubation period, the enhanced intracellular ROS level in rBMSCs on the fully fluorinated graphene gives rise to the decrease of cell viability. It was found that there is no statistical difference in the activity of alkaline phosphatase (ALP) and matrix mineralization of rBMSCs on pristine graphene, partially fluorinated graphene and fluorographene. In addition, the introduction of fluorine into pristine graphene plane reduced the adhesion and aggregation of blood platelets due to the attenuation of pi-pi interaction between material surface and blood protein. The findings in this work revealed that partial fluorinated graphene exhibited better antibacterial ability and cytocompatibility, outperforming pristine graphene and fluorographene.
WOS研究方向Biophysics ; Chemistry ; Materials Science
语种英语
出版者ELSEVIER SCIENCE BV
源URL[http://ir.sic.ac.cn/handle/331005/27436]  
专题中国科学院上海硅酸盐研究所
推荐引用方式
GB/T 7714
Geng, Hao,Wang, Tianbo,Cao, Huiliang,et al. Antibacterial ability, cytocompatibility and hemocompatibility of fluorinated graphene[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2019,173:681.
APA Geng, Hao,Wang, Tianbo,Cao, Huiliang,Zhu, Hongqin,Di, Zengfeng,&Liu, Xuanyong.(2019).Antibacterial ability, cytocompatibility and hemocompatibility of fluorinated graphene.COLLOIDS AND SURFACES B-BIOINTERFACES,173,681.
MLA Geng, Hao,et al."Antibacterial ability, cytocompatibility and hemocompatibility of fluorinated graphene".COLLOIDS AND SURFACES B-BIOINTERFACES 173(2019):681.

入库方式: OAI收割

来源:上海硅酸盐研究所

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