Semiparametric estimation of differences in treatment-specific recurrent event means with a terminal event
文献类型：期刊论文
| 作者 | Sun, Xiaowei1,2; Sun, Liuquan1,2
|
| 刊名 | STATISTICS AND ITS INTERFACE
 |
| 出版日期 | 2019 |
| 卷号 | 12期号:1页码:1-9 |
| 关键词 | Additive models Marginal mean Recurrent events Semiparametric method Terminal event Treatment effect |
| ISSN号 | 1938-7989 |
| 英文摘要 | Recurrent event data often arise from biomedical studies and a terminal event may preclude further occurrence of recurrent events. In comparing treatments, the marginal mean is frequently of interest, and treatment-specific differences in the mean number of events are often not constant over time. In this article, we propose a semiparametric method to compare treatment-specific recurrent event means by combining an additive hazards model for the terminal event and an additive rates model for the conditional recurrent event rate. The treatment effect is measured by the difference between treatment-specific recurrent event means. Estimation procedures are developed for the measure and the asymptotic properties of the proposed estimators are established. The finite sample performance of the proposed estimators is examined through simulation studies, and an application to a bladder cancer study demonstrates the usefulness of our method. |
| 资助项目 | National Natural Science Foundation of China[11771431] ; National Natural Science Foundation of China[11690015] ; Key Laboratory of RCSDS, CAS[2008DP173182] |
| WOS研究方向 | Mathematical & Computational Biology ; Mathematics |
| 语种 | 英语 |
| WOS记录号 | WOS:000460758600001 |
| 出版者 | INT PRESS BOSTON, INC |
| 源URL | [http://ir.amss.ac.cn/handle/2S8OKBNM/34193]  |
| 专题 | 应用数学研究所 |
| 通讯作者 | Sun, Liuquan |
| 作者单位 | 1.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Xiaowei,Sun, Liuquan. Semiparametric estimation of differences in treatment-specific recurrent event means with a terminal event[J]. STATISTICS AND ITS INTERFACE,2019,12(1):1-9. |
| APA | Sun, Xiaowei,&Sun, Liuquan.(2019).Semiparametric estimation of differences in treatment-specific recurrent event means with a terminal event.STATISTICS AND ITS INTERFACE,12(1),1-9. |
| MLA | Sun, Xiaowei,et al."Semiparametric estimation of differences in treatment-specific recurrent event means with a terminal event".STATISTICS AND ITS INTERFACE 12.1(2019):1-9. |
入库方式： OAI收割
来源：数学与系统科学研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。