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The Cox-Aalen model for recurrent-event data with a dependent terminal event

文献类型：期刊论文

作者Qu, Lianqiang2; Sun, Liuquan1
刊名STATISTICA NEERLANDICA
出版日期2019-05-01
卷号73期号:2页码:234-255
关键词Cox-Aalen model estimating equation recurrent events share frailty terminal event
ISSN号0039-0402
DOI10.1111/stan.12167
英文摘要Recurrent events with a dependent terminal event arise frequently in a wide variety of fields. In this paper, we propose a new joint model to analyze these data and model the dependence between recurrent and terminal events through shared gamma frailty. Specifically, a Cox-Aalen rate frailty model is specified for the recurrent event, and an additive hazards frailty model is specified for the terminal event. An estimating equation approach is developed for the parameters in the joint model, and the asymptotic properties of the proposed estimators are established. Simulation studies demonstrate that the proposed estimators perform well with finite samples. An application to a medical cost study of chronic heart failure patients is illustrated.
资助项目National Natural Science Foundation of China[11771431] ; National Natural Science Foundation of China[11690015] ; Key Laboratory of Random Complex Structures and Data Science, Chinese Academy of Sciences[2008DP173182] ; Fundamental Research Funds for the Central Universities[20205180090]
WOS研究方向Mathematics
语种英语
WOS记录号WOS:000466377800006
出版者WILEY
源URL[http://ir.amss.ac.cn/handle/2S8OKBNM/34604]  
专题应用数学研究所
通讯作者Sun, Liuquan
作者单位1.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing 100190, Peoples R China
2.Cent China Normal Univ, Sch Math & Stat, Wuhan 430079, Hubei, Peoples R China
推荐引用方式
GB/T 7714		 Qu, Lianqiang,Sun, Liuquan. The Cox-Aalen model for recurrent-event data with a dependent terminal event[J]. STATISTICA NEERLANDICA,2019,73(2):234-255.
APA Qu, Lianqiang,&Sun, Liuquan.(2019).The Cox-Aalen model for recurrent-event data with a dependent terminal event.STATISTICA NEERLANDICA,73(2),234-255.
MLA Qu, Lianqiang,et al."The Cox-Aalen model for recurrent-event data with a dependent terminal event".STATISTICA NEERLANDICA 73.2(2019):234-255.

入库方式： OAI收割

来源：数学与系统科学研究院

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