中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A cluster-adjusted rank-based test for a clinical trial concerning multiple endpoints with application to dietary intervention assessment

文献类型:期刊论文

作者Zhang, Wei1; Liu, Aiyi1; Tang, Larry L.2,3; Li, Qizhai4
刊名BIOMETRICS
出版日期2019-09-01
卷号75期号:3页码:821-830
关键词generalized Behrens-Fisher hypothesis multivariate distributions nonparametrics rank statistics type I errors power of test
ISSN号0006-341X
DOI10.1111/biom.13029
英文摘要Multiple endpoints are often naturally clustered based on their scientific interpretations. Tests that compare these clustered outcomes between independent groups may lose efficiency if the cluster structures are not properly accounted for. For the two-sample generalized Behrens-Fisher hypothesis concerning multiple endpointswe propose a cluster-adjusted multivariate test procedure for the comparison and demonstrate its gain in efficiency over test procedures that ignore the clusters. Data from a dietary intervention trial are used to illustrate the methods.
资助项目Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health ; Intramural Research Program of the National Institutes of Health ; US Social Security Administration ; Special National Key Research and Development Plan[2016YFD0400206] ; Breakthrough Project of Strategic Priority Program of the Chinese Academy of Sciences[XDB13040600] ; National Nature Science Foundation of China[11722113]
WOS研究方向Life Sciences & Biomedicine - Other Topics ; Mathematical & Computational Biology ; Mathematics
语种英语
WOS记录号WOS:000488608100010
出版者WILEY
源URL[http://ir.amss.ac.cn/handle/2S8OKBNM/35873]  
专题系统科学研究所
通讯作者Li, Qizhai
作者单位1.Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Biostat & Bioinformat Branch, NIH, Bethesda, MD USA
2.George Mason Univ, Dept Stat, Fairfax, VA 22030 USA
3.Natl Inst Hlth Clin Ctr, Rehabil Med Dept, Bethesda, MD USA
4.Chinese Acad Sci, Acad Math & Syst Sci, NCMIS, LSC, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Wei,Liu, Aiyi,Tang, Larry L.,et al. A cluster-adjusted rank-based test for a clinical trial concerning multiple endpoints with application to dietary intervention assessment[J]. BIOMETRICS,2019,75(3):821-830.
APA Zhang, Wei,Liu, Aiyi,Tang, Larry L.,&Li, Qizhai.(2019).A cluster-adjusted rank-based test for a clinical trial concerning multiple endpoints with application to dietary intervention assessment.BIOMETRICS,75(3),821-830.
MLA Zhang, Wei,et al."A cluster-adjusted rank-based test for a clinical trial concerning multiple endpoints with application to dietary intervention assessment".BIOMETRICS 75.3(2019):821-830.

入库方式: OAI收割

来源:数学与系统科学研究院

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