Abietane diterpenoids from Caryopteris incana (Thunb.) Miq
文献类型：期刊论文
| 作者 | Zhao, Sen-Miao; Chou, Gui-Xin; Yang, Qing-Shan; Wang, Wei; Zhou, Jian-Li |
| 刊名 | Organic & biomolecular chemistry
 |
| 出版日期 | 2016-04-14 |
| 卷号 | 14期号:14页码:3510-20 |
| ISSN号 | 1477-0539 |
| DOI | 10.1039/c6ob00139d |
| 文献子类 | Article |
| 英文摘要 | Twelve new diterpenes, caryopincaolide A-L (1-4, 11-12, 16-19, 27-28), together with twenty-eight known diterpenes, have been isolated from the whole plant of Caryopteris incana (Thunb.) Miq. Their structures were elucidated on the basis of 1D and 2D NMR, IR, X-ray crystal diffraction and mass spectroscopic data, as well as ECD calculations. All compounds were tested for in vitro dipeptidyl peptidase IV (DPP-IV) inhibitory activity, with compounds 3, 4, 28, 29, and 40 exhibiting DPP-IV inhibitory effects with IC50 values ranging from 54.2 to 228.9 μM. Compounds 1, 3 and 4 also showed potent activity toward the inhibition of the growth of human cancer cells and 1 can induce apoptosis in Hey and A-549 cells. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/266355]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Zhao, Sen-Miao |
| 作者单位 | Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China |
| 推荐引用方式 GB/T 7714 | Zhao, Sen-Miao,Chou, Gui-Xin,Yang, Qing-Shan,et al. Abietane diterpenoids from Caryopteris incana (Thunb.) Miq[J]. Organic & biomolecular chemistry,2016,14(14):3510-20. |
| APA | Zhao, Sen-Miao,Chou, Gui-Xin,Yang, Qing-Shan,Wang, Wei,&Zhou, Jian-Li.(2016).Abietane diterpenoids from Caryopteris incana (Thunb.) Miq.Organic & biomolecular chemistry,14(14),3510-20. |
| MLA | Zhao, Sen-Miao,et al."Abietane diterpenoids from Caryopteris incana (Thunb.) Miq".Organic & biomolecular chemistry 14.14(2016):3510-20. |
入库方式： OAI收割
来源：上海药物研究所
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