Rapid Characterization of Constituents in Tribulus terrestris from Different Habitats by UHPLC/Q-TOF MS
文献类型：期刊论文
| 作者 | Zheng, Wei1; Wang, Fangxu1; Zhao, Yang1; Sun, Xinguang1; Kang, Liping1; Fan, Ziquan2; Qiao, Lirui2; Yan, Renyi1; Liu, Shuchen1; Ma, Baiping1 |
| 刊名 | Journal of the American Society for Mass Spectrometry
 |
| 出版日期 | 2017-11 |
| 卷号 | 28期号:11页码:2302-2318 |
| ISSN号 | 1879-1123 |
| DOI | 10.1007/s13361-017-1761-5 |
| 文献子类 | Article |
| 英文摘要 | A strategy for rapid identification of the chemical constituents from crude extracts of Tribulus terrestris was proposed using an informatics platform for the UHPLC/Q-TOF MS data analyses. This strategy mainly utilizes neutral losses, characteristic fragments, and in-house library to rapidly identify the structure of the compounds. With this strategy, rapid characterization of the chemical components of T. terrestris from Beijing, China was successfully achieved. A total of 82 steroidal saponins and nine flavonoids were identified or tentatively identified from T. terrestris. Among them, 15 new components were deduced based on retention times and characteristic MS fragmentation patterns. Furthermore, the chemical components of T. terrestris, including the other two samples from Xinjiang Uygur Autonomous region, China, and Rome, Italy, were also identified with this strategy. Altogether, 141 chemical components were identified from these three samples, of which 39 components were identified or tentatively identified as new compounds, including 35 groups of isomers. It demonstrated that this strategy provided an efficient protocol for the rapid identification of chemical constituents in complex samples such as traditional Chinese medicines (TCMs) by UHPLC/Q-TOF MS with informatics platform. Graphical Abstract ᅟ. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/266552]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Ma, Baiping |
| 作者单位 | 1.Beijing Institute of Radiation Medicine, No. 27 Taiping Road, Beijing, 100850, China; 2.Waters Technology (Shanghai) Co., Ltd, Shanghai, 201206, China |
| 推荐引用方式 GB/T 7714 | Zheng, Wei,Wang, Fangxu,Zhao, Yang,et al. Rapid Characterization of Constituents in Tribulus terrestris from Different Habitats by UHPLC/Q-TOF MS[J]. Journal of the American Society for Mass Spectrometry,2017,28(11):2302-2318. |
| APA | Zheng, Wei.,Wang, Fangxu.,Zhao, Yang.,Sun, Xinguang.,Kang, Liping.,...&Ma, Baiping.(2017).Rapid Characterization of Constituents in Tribulus terrestris from Different Habitats by UHPLC/Q-TOF MS.Journal of the American Society for Mass Spectrometry,28(11),2302-2318. |
| MLA | Zheng, Wei,et al."Rapid Characterization of Constituents in Tribulus terrestris from Different Habitats by UHPLC/Q-TOF MS".Journal of the American Society for Mass Spectrometry 28.11(2017):2302-2318. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。