Structure characterization of an arabinogalactan from green tea and its anti-diabetic effect
文献类型：期刊论文
| 作者 | Wang, Huijun; Shi, Songshan; Bao, Bin; Li, Xiaojun; Wang, Shunchun |
| 刊名 | Carbohydrate polymers
 |
| 出版日期 | 2015-06-25 |
| 卷号 | 124页码:98-108 |
| ISSN号 | 1879-1344 |
| DOI | 10.1016/j.carbpol.2015.01.070 |
| 文献子类 | Article |
| 英文摘要 | A water-soluble polysaccharide, 7WA, with an average molecular mass of 7.1×10(4)Da, was isolated from the leaves of green tea. Monosaccharide composition analysis indicated that 7WA mainly contained Arabinose and Galactose in the molar ratio of 1.0:0.96. By using the methods of methylation analysis, partial hydrolysis, and NMR, 7WA was characterized to possess a backbone consisting of 1,3- and 1,6-linked galactopyranosyl residues, with branches attached to O-3 of 1,6-linked galactose residues, and O-4 and O-6 of 1,3-linked galactose residues. The results of glucose-stimulated insulin secretion (GSIS) showed that 7WA significantly augmented insulin secretion at high glucose level (25mM), however, such effect was not seen at low glucose level (5mM). The mechanism study results indicated 7WA, a type II arabinogalactan from Green Tea, enhances GSIS through cAMP-PKA pathway. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/266573]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Wang, Shunchun |
| 作者单位 | The MOE Key Laboratory for Standardization of Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China |
| 推荐引用方式 GB/T 7714 | Wang, Huijun,Shi, Songshan,Bao, Bin,et al. Structure characterization of an arabinogalactan from green tea and its anti-diabetic effect[J]. Carbohydrate polymers,2015,124:98-108. |
| APA | Wang, Huijun,Shi, Songshan,Bao, Bin,Li, Xiaojun,&Wang, Shunchun.(2015).Structure characterization of an arabinogalactan from green tea and its anti-diabetic effect.Carbohydrate polymers,124,98-108. |
| MLA | Wang, Huijun,et al."Structure characterization of an arabinogalactan from green tea and its anti-diabetic effect".Carbohydrate polymers 124(2015):98-108. |
入库方式： OAI收割
来源：上海药物研究所
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