Polyketides from the fungus Penicillium decumbens
文献类型：期刊论文
| 作者 | Lin, Sheng1; Wu, Yu-Zhuo2; Chen, Ke-Yv1; Ye, Ji1; Yang, Xian-Wen1; Zhang, Wei-Dong1 |
| 刊名 | Journal of Asian natural products research
 |
| 出版日期 | 2018-05 |
| 卷号 | 20期号:5页码:445-450 |
| ISSN号 | 1477-2213 |
| DOI | 10.1080/10286020.2018.1424139 |
| 文献子类 | Article |
| 英文摘要 | Two new polyketides, 3,11-dihydroxy-6,8-dimethyldodecanoic acid (1) and trichopyrone B (2), together with two known polyketides, sorbicillin (3) and penicillone A (4), have been isolated from the cultures broth of the fungus Penicillium decumbens. Their structures were elucidated by extensive spectroscopic analysis. All isolated compounds were evaluated for their antibacterial and cytotoxic activities. Of these, compound 3 showed antifungal activity toward Candida albicans Y0109 with a MIC value of 50 μM. Moreover, compounds 3 and 4 exhibited selective cytotoxicity against the human hepatocellular carcinoma (QGY-7703) cell line with the IC values of 32.5 and 22.8 μM, respectively. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/266591]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.a Department of Natural Product Chemistry, School of Pharmacy , Second Military Medical University , Shanghai 200433 , China; 2.b State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China |
| 推荐引用方式 GB/T 7714 | Lin, Sheng,Wu, Yu-Zhuo,Chen, Ke-Yv,et al. Polyketides from the fungus Penicillium decumbens[J]. Journal of Asian natural products research,2018,20(5):445-450. |
| APA | Lin, Sheng,Wu, Yu-Zhuo,Chen, Ke-Yv,Ye, Ji,Yang, Xian-Wen,&Zhang, Wei-Dong.(2018).Polyketides from the fungus Penicillium decumbens.Journal of Asian natural products research,20(5),445-450. |
| MLA | Lin, Sheng,et al."Polyketides from the fungus Penicillium decumbens".Journal of Asian natural products research 20.5(2018):445-450. |
入库方式： OAI收割
来源：上海药物研究所
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