Salicylate induces reactive oxygen species and reduces ultraviolet C susceptibility in Staphylococcus aureus
文献类型：期刊论文
| 作者 | Cai, Jia-Yi3; Wang, Yuan-Yuan3; Ma, Kai3; Hou, Yong-Na3; Yao, Guo-Dong4; Hayashi, Toshihiko3; Itoh, Kikuji5; Tashiro, Shin-Ichi1; Onodera, Satoshi2; Ikejima, Takashi3 |
| 刊名 | FEMS microbiology letters
 |
| 出版日期 | 2018-04-01 |
| 卷号 | 365期号:8 |
| ISSN号 | 1574-6968 |
| DOI | 10.1093/femsle/fny056 |
| 文献子类 | Article |
| 英文摘要 | This study demonstrates that growth of Staphylococcus aureus in the presence of salicylate reduces ultraviolet C (UVC)-induced cell death and increases the generation of reactive oxygen species (ROS). In addition, compounds that scavenge ROS (N-acetylcysteine, glutathione, catalase and superoxide dismutase) reverse the increased UVC survival induced by growth in the presence of salicylate, while ROS donors (tert-butylhydroperoxide, H2O2 and NaClO) enhance survival of salicylate challenged cultures. Collectively, these findings suggest that ROS production induced by growth in the presence of salicylate protects S. aureus from UVC-induced cell death. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/266608]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.Department of Medical Education & Primary Care, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan; 2.Department of Clinical and Pharmaceutical Sciences, Showa Pharmaceutical University, Tokyo 194-8543, Japan 3.China-Japan Research Institute of Medical and Pharmaceutical Sciences, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China; 4.School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery (Ministry of Education), Shenyang Pharmaceutical University, Shenyang 110016, China; 5.Biochemical Center, Japan SLC, Inc., Shizuoka 431-1103, Japan; |
| 推荐引用方式 GB/T 7714 | Cai, Jia-Yi,Wang, Yuan-Yuan,Ma, Kai,et al. Salicylate induces reactive oxygen species and reduces ultraviolet C susceptibility in Staphylococcus aureus[J]. FEMS microbiology letters,2018,365(8). |
| APA | Cai, Jia-Yi.,Wang, Yuan-Yuan.,Ma, Kai.,Hou, Yong-Na.,Yao, Guo-Dong.,...&Ikejima, Takashi.(2018).Salicylate induces reactive oxygen species and reduces ultraviolet C susceptibility in Staphylococcus aureus.FEMS microbiology letters,365(8). |
| MLA | Cai, Jia-Yi,et al."Salicylate induces reactive oxygen species and reduces ultraviolet C susceptibility in Staphylococcus aureus".FEMS microbiology letters 365.8(2018). |
入库方式： OAI收割
来源：上海药物研究所
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