Monoterpene derivatives with anti-allergic activity from red peony root, the root of Paeonia lactiflora
文献类型：期刊论文
| 作者 | Shi, Yan-Hong3 ; Zhu, Shu3; Ge, Yue-Wei3; He, Yu-Min3; Kazuma, Kohei4; Wang, Zhengtao2; Yoshimatsu, Kayo1; Komatsu, Katsuko3
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| 刊名 | Fitoterapia
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| 出版日期 | 2016-01 |
| 卷号 | 108页码:55-61 |
| ISSN号 | 1873-6971 |
| DOI | 10.1016/j.fitote.2015.11.011 |
| 文献子类 | Article |
| 英文摘要 | The methanolic extract and its subfractions from red peony root, the dried roots of Paeonia lactiflora Pallas showed potent antiallergic effects, as inhibition of immunoglobulin E (IgE)-mediated degranulation in rat basophil leukemia (RBL)-2H3 cells. Bioassay-guided fractionation led to the isolation of 16 monoterpene derivatives, including 3 new compounds, paeoniflorol (1), 4'-hydroxypaeoniflorigenone (2) and 4-epi-albiflorin (3), together with 13 known ones (4-16). The chemical structures of the new compounds were elucidated on the basis of spectroscopic and chemical evidences. Among the isolated monoterpene derivatives, nine compounds showed potent anti-allergic effects and compound 1 was the most effective. A primary structure-activity relationship of monoterpene derivatives was discussed. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/266627]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Zhu, Shu; Komatsu, Katsuko |
| 作者单位 | 1.Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation, Health and Nutrition, Ibaraki 305-0843, Japan 2.The MOE Key laboratory of Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201-203, China; 3.Division of Pharmacognosy, Department of Medicinal Resources, Institute of Natural Medicine, University of Toyama, Toyama 930-0194, Japan; 4.Division of Kampo-Pharmaceutics, Department of Medicinal Resources, Institute of Natural Medicine, University of Toyama, Toyama 930-0194, Japan; |
| 推荐引用方式 GB/T 7714 | Shi, Yan-Hong,Zhu, Shu,Ge, Yue-Wei,et al. Monoterpene derivatives with anti-allergic activity from red peony root, the root of Paeonia lactiflora[J]. Fitoterapia,2016,108:55-61. |
| APA | Shi, Yan-Hong.,Zhu, Shu.,Ge, Yue-Wei.,He, Yu-Min.,Kazuma, Kohei.,...&Komatsu, Katsuko.(2016).Monoterpene derivatives with anti-allergic activity from red peony root, the root of Paeonia lactiflora.Fitoterapia,108,55-61. |
| MLA | Shi, Yan-Hong,et al."Monoterpene derivatives with anti-allergic activity from red peony root, the root of Paeonia lactiflora".Fitoterapia 108(2016):55-61. |
入库方式： OAI收割
来源：上海药物研究所
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