Signal transduction by protein tyrosine kinases and antitumor agents
文献类型：会议论文
| 作者 | Mao, Yong-Jun; Li, Hai-Hong; Li, Jian-Feng ; Shen, Jing-Shan
|
| 出版日期 | 2008-04 |
| 卷号 | 43 |
| 期号 | 4 |
| 页码 | 323-34 |
| 英文摘要 | Intracellular signal transduction plays an important role in the process of cellular metabolism, segmentation, differentiation, biological behaviour and cell death. Overactive signal transduction relates to tumor development and progression. Signaling pathways operated by protein tyrosine kinases (PTKs) will be illuminated here briefly. The Ras/Raf/MAPK and PI-3K/Akt pathways through receptor protein tyrosine kinases (RTKs), the Src, Bcr-Abl and JAK/STAT pathways by non-receptor protein tyrosine kinases (nrPTKs) are shown separately. Antitumor agents targeting the key proteins involved in the above five signalling routes are also summarized in this review. |
| 会议录 | Yao xue xue bao = Acta pharmaceutica Sinica
 |
| 文献子类 | Meeting Abstract;Article;Review |
| 语种 | 中文 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/266879]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China |
| 推荐引用方式 GB/T 7714 | Mao, Yong-Jun,Li, Hai-Hong,Li, Jian-Feng,et al. Signal transduction by protein tyrosine kinases and antitumor agents[C]. 见:. |
入库方式： OAI收割
来源：上海药物研究所
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