Diagnostic ion-oriented identification and simultaneous quantification of chemical components in Allium chinense G. Don
文献类型：期刊论文
| 作者 | Qin, Zifei1,3,4; Lin, Pei3; Yao, Zhihong3,4,5; Chen, Zilin3; Yu, Yang3,4; Dai, Yi3,4; He, Xiangjiu6; Zhou, Hua2; Yao, Xinsheng2,3,4 |
| 刊名 | Journal of Separation Science
 |
| 出版日期 | 2018-12 |
| 卷号 | 41期号:23页码:4253-4271 |
| ISSN号 | 16159306 |
| DOI | 10.1002/jssc.201800476 |
| 文献子类 | Article |
| 英文摘要 | Allium chinense G. Don, a popular edible condiment with reputation of Ganoderma lucidum in vegetables, exerts significant health effects for treating coronary disease but chemical compounds and corresponding contents still remain unclear. In this study, a total of 80 chemical compounds were detected in Allium chinense extracts based on a summarized fragmentation pattern, of which 32 were unambiguously identified with reference standards. Furthermore, a practical and feasible method was developed and validated for simultaneous quantification of 18 chemical compounds, of which 17 compounds were steroidal saponins, by ultra-high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry. In addition, it was known that the contents of quantitative compounds varied significantly among multiple Allium chinense samples. Moreover, chemometric analysis results suggested that chinenoside I, macrostemonoside B, and chinenoside II were the most important markers responsible for poor consistency. Taken altogether, this study would be helpful for the chemical authentication and quality control of Allium chinense samples. |
| 语种 | 英语 |
| 出版者 | Wiley-VCH Verlag |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/266967]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Yao, Zhihong |
| 作者单位 | 1.Department of Pharmacy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; 2.State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, China 3.College of Pharmacy, Jinan University, Guangzhou, China; 4.Guangdong Provincial Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou, China; 5.State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China; 6.School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China; |
| 推荐引用方式 GB/T 7714 | Qin, Zifei,Lin, Pei,Yao, Zhihong,et al. Diagnostic ion-oriented identification and simultaneous quantification of chemical components in Allium chinense G. Don[J]. Journal of Separation Science,2018,41(23):4253-4271. |
| APA | Qin, Zifei.,Lin, Pei.,Yao, Zhihong.,Chen, Zilin.,Yu, Yang.,...&Yao, Xinsheng.(2018).Diagnostic ion-oriented identification and simultaneous quantification of chemical components in Allium chinense G. Don.Journal of Separation Science,41(23),4253-4271. |
| MLA | Qin, Zifei,et al."Diagnostic ion-oriented identification and simultaneous quantification of chemical components in Allium chinense G. Don".Journal of Separation Science 41.23(2018):4253-4271. |
入库方式： OAI收割
来源：上海药物研究所
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