Screen for the quorum sensing inhibitory activity from marine bacterial isolates
文献类型：期刊论文
| 作者 | Ding Biting2; Lu Yeqian2; Dong Kunming2; Wang Xiaozhi2; Zhou Xiaojian2; Jin Cuili2; Miao Li1 |
| 刊名 | Microbiology
 |
| 出版日期 | 2012 |
| 卷号 | 39期号:1页码:2-8 |
| 关键词 | Quorum sensing inhibitory activity Chromobacterium violaceum Marine bacteria |
| ISSN号 | 0253-2654 |
| 其他题名 | 具有群体感应抑制活性的海洋细菌的筛选 |
| 文献子类 | Article |
| 英文摘要 | [Objective] Quorum sensing inhibitory activity of some marine bacterial isolates was investigated to provide potential novel origins of natural products for the promising antibacterial therapeutic approaches targeting on the quorum sensing system of some pathogens.[Methods] In this study,we used Chromobacterium violaceum as the report-strain to screen for the quorum sensing inhibitory activity from some marine bacterial isolates by disc diffusion assay and double-layer soft agar assay.[Results] In total,272 bacteria strains isolated from the sponge tissues collected around the San Juan Island had been tested.The results showed that 51 isolates exhibited the quorum sensing inhibitory activity.Among the active strains,bacterium No.74 had the strongest activity,which is deserved the further study on the isolation and identification of quorum sensing inhibitors.[Conclusion] Many marine bacterial isolates exhibit quorum sensing inhibitory,which indicated that marine bacteria are also a potential source for the natural quorum sensing inhibitors. |
| 资助项目 | 国家自然科学基金项目[00000000] ; 新药研究国家重点实验室开放基金项目[00000000] ; 江苏省高校自然科学基金项目[00000000] |
| WOS研究方向 | Microbiology (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:4420101 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/267854]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.Key Laboratory of Drug Research,Shanghai Institute of Material Medical,Chinese Academy of Sciences, Shanghai 201203, China. 2.School of Environmental Science and Engineering,Yangzhou University, Yangzhou, Yangzhou, Jiangsu 225127, China.; |
| 推荐引用方式 GB/T 7714 | Ding Biting,Lu Yeqian,Dong Kunming,et al. Screen for the quorum sensing inhibitory activity from marine bacterial isolates[J]. Microbiology,2012,39(1):2-8. |
| APA | Ding Biting.,Lu Yeqian.,Dong Kunming.,Wang Xiaozhi.,Zhou Xiaojian.,...&Miao Li.(2012).Screen for the quorum sensing inhibitory activity from marine bacterial isolates.Microbiology,39(1),2-8. |
| MLA | Ding Biting,et al."Screen for the quorum sensing inhibitory activity from marine bacterial isolates".Microbiology 39.1(2012):2-8. |
入库方式： OAI收割
来源：上海药物研究所
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