TIEC and its function in TGF-beta-Smads signling pathways
文献类型：期刊论文
| 作者 | Min Ping2; Jin Wei2; Chen Shan2; Mao Zhengyin3; Lu He1 |
| 刊名 | Chinese Bulletin of Life Sciences
 |
| 出版日期 | 2004 |
| 卷号 | 16期号:2页码:84-89 |
| 关键词 | TIEG TIEG |
| ISSN号 | 1004-0374 |
| 其他题名 | TIEG及其在TGF-beta-Smads通路中的作用 |
| 文献子类 | Review |
| 英文摘要 | TGF-fJ-inducible early gene(TIEG) is a member of the Spl-like transcription factor family, TIEG1 and TIEG2 belong to a same subfamily. The stability of TIEG1 is associated with ubiqiutin-proteasomal pathways. The 3 zinc-finger motif in C-terminal and the transcriptional repression domain in N-terminal of TIEG1 are important to keep its normal function. As the immediate early gene induced by TGF-P, TIEG altered the cell morphogenesis, inhibited cell proliferation and induced cell apoptosis. TIEG1 plays its role through the Smads, and the feedback formed by Smad7 and TIEG1 is very important in the TGF-beta-Smads signaling pathways. |
| WOS研究方向 | Life Sciences & Biomedicine - Other Topics (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:1630905 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268402]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.Le pole francochinois du science du vivant et geoique,Rujin hospital, Shanghai 200025, China. 2.Shanghai Institute of Materia Medica,Chinese Academy of Sciences, Shanghai 201203, China.; 3.Beijing Drug Administration, Beijing 100016, China.; |
| 推荐引用方式 GB/T 7714 | Min Ping,Jin Wei,Chen Shan,et al. TIEC and its function in TGF-beta-Smads signling pathways[J]. Chinese Bulletin of Life Sciences,2004,16(2):84-89. |
| APA | Min Ping,Jin Wei,Chen Shan,Mao Zhengyin,&Lu He.(2004).TIEC and its function in TGF-beta-Smads signling pathways.Chinese Bulletin of Life Sciences,16(2),84-89. |
| MLA | Min Ping,et al."TIEC and its function in TGF-beta-Smads signling pathways".Chinese Bulletin of Life Sciences 16.2(2004):84-89. |
入库方式： OAI收割
来源：上海药物研究所
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