In vitro susceptibilities of Mycoplasma and Ureaplasma to a derivative (YH7) of levofloxacin
文献类型：期刊论文
| 作者 | Ye H(叶辉); Yang YS(杨玉社) ; Wu JM(武济民); Chen KX(陈凯先); Ji RY(嵇汝运)
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| 刊名 | Chinese Journal of Antibiotics
 |
| 出版日期 | 2002 |
| 卷号 | 27期号:10页码:617 |
| 关键词 | Mycoplasma Ureaplasma microbial sensitivity levofloxacin YH7 YH7 |
| ISSN号 | 1001-8689 |
| 其他题名 | 枝原体和尿原体对左氧氟沙星衍生物（YH7）的体外敏感性研究 |
| 文献子类 | Article |
| 英文摘要 | The in vitro susceptibilities of Mycoplasma and Ureaplasma to the derivative of levofloxacin (YH7) and referential quinolones, macrolides and tetracyclines were determined by microdilution method. Results showed that the minimum inhibition concentration (MIC) of YH7 for Ureaplasma urealyticum (Uu: 0.125 mg/L), Mycoplasma hominis (Mh: 0.5 mg/L), M.orale (M. ora: 0.25 mg/L) and M. salivarium (M. sal: 0.125 mg/L) were similar to those of macrolides (erythromyein, leucomycin) and the activity of YH7 were 2～16 folds more potent than those of ofloxacin. Uu, Mh could easily induce resistance to erythromycin and tetracycline. They did not easily produce resistance to YH7 and josamycin. Tetracycline- resistance (Tc~r) or erythromycin-resistance (EM~r) strains of Uu (or Mh) had cross-resistance to erythromycin or tetracycline. However, they had no cross-resistance to YH7 and josamycin. |
| 资助项目 | 国家自然科学基金（No29672037)资助项目[00000000] |
| WOS研究方向 | Pharmacology & Pharmacy (provided by Clarivate Analytics) |
| 语种 | 英语 |
| CSCD记录号 | CSCD:1082425 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268480]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.Shanghai Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, ShangHai 200032, China. 2.Department of Life Sciences and Technology, Nantong Normal College, Nantong, Jiangsu 226007, China.; |
| 推荐引用方式 GB/T 7714 | Ye H,Yang YS,Wu JM,et al. In vitro susceptibilities of Mycoplasma and Ureaplasma to a derivative (YH7) of levofloxacin[J]. Chinese Journal of Antibiotics,2002,27(10):617. |
| APA | 叶辉,杨玉社,武济民,陈凯先,&嵇汝运.(2002).In vitro susceptibilities of Mycoplasma and Ureaplasma to a derivative (YH7) of levofloxacin.Chinese Journal of Antibiotics,27(10),617. |
| MLA | 叶辉,et al."In vitro susceptibilities of Mycoplasma and Ureaplasma to a derivative (YH7) of levofloxacin".Chinese Journal of Antibiotics 27.10(2002):617. |
入库方式： OAI收割
来源：上海药物研究所
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