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Effect of different fractions from DANGGUI BUXUE TANG on immunological function in normal and blood-deficiency mouse
文献类型：期刊论文
| 作者 | Wang Yanping1; Li Xiaoyu1; Song Chunqing2; Chen Changxun2; Hu Zhibi2 |
| 刊名 | Chinese Traditional and Herbal Drugs
 |
| 出版日期 | 2002 |
| 卷号 | 33期号:2页码:135-138 |
| 关键词 | DANGGUI BUXUE TANG Astragalus membranaceus (Fish) Bunge angelica sinensis (Oliv.) Diels immunomodulation blood-deficiency model |
| ISSN号 | 0253-2670 |
| 其他题名 | 当归补血汤中不同组分对正常及血虚小鼠免疫功能的影响 |
| 文献子类 | Article |
| 英文摘要 | Object To study the immunomodulatory effect of seven fractions from DANGGUI BUX-UE TANG in normal and blood-deficiency mouse. Methods The proliferation of T, B lymphocyte was measured by MTT assay; the activity of splenocyte antibody was determined by spectroscopic assay; the blood-deficiency model was prepared by injection of acetyl phenylhydrazine and cyclophosphamide. Results Four fractions from Astragalus membranaceus (Fisch. ) Bunge all promoted proliferation of T and B lym-phocyte and antibody production. Three fractions from Angelica sinensis (Oliv. ) Diels had different effects at 200 mg/kg po in vivo, but they all showed significant immunomodulatory effects on blood-deficiency mouse. In vitro, volatile oil, flavone and saponin from A. membranaceus and volatile oil > flavone from A. sinensis exhibited fine dual-immunomodulatory effects, polysaccharide from both herbs showed well con-centration-dependent immunomodulatory effects at the doses of 2. 5~250 /-ig/mL. Conclusion There are different immunomodulatory effects in the different fractions from DANGGUI BUXUE TANG. |
| 资助项目 | 九五国家攀登计划预选项目[00000000] ; 中药现代化关键问题的基础研究，编号98pd09[00000000] |
| WOS研究方向 | General & Internal Medicine (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:1105712 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268488]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China.; 2.Shanghai University of TCM, Shanghai 200032, China. |
| 推荐引用方式 GB/T 7714 | Wang Yanping,Li Xiaoyu,Song Chunqing,et al. Effect of different fractions from DANGGUI BUXUE TANG on immunological function in normal and blood-deficiency mouse[J]. Chinese Traditional and Herbal Drugs,2002,33(2):135-138. |
| APA | Wang Yanping,Li Xiaoyu,Song Chunqing,Chen Changxun,&Hu Zhibi.(2002).Effect of different fractions from DANGGUI BUXUE TANG on immunological function in normal and blood-deficiency mouse.Chinese Traditional and Herbal Drugs,33(2),135-138. |
| MLA | Wang Yanping,et al."Effect of different fractions from DANGGUI BUXUE TANG on immunological function in normal and blood-deficiency mouse".Chinese Traditional and Herbal Drugs 33.2(2002):135-138. |
入库方式： OAI收割
来源：上海药物研究所
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