Effect of piracetam per os on physiological functions of divers during the simulated 65 m heliox saturation dive
文献类型：期刊论文
| 作者 | Li Ci; Fang Yiqun; He Jia; Liu Yuming; Chen Ruiyong; Zhao Liangcai; Yang Tao; Lv Jun; Lin Donghai; Xiao Weibing |
| 刊名 | Chinese Journal of Nautical Medicine and Hyperbaric Medicine
 |
| 出版日期 | 2014 |
| 卷号 | 21期号:2页码:76-79 |
| 关键词 | Saturation dive Helium-oxygen Piracetam Blood pressure Aspartate aminotransferase Alanine aminotransferase |
| ISSN号 | 1009-6906 |
| 其他题名 | 脑复康对模拟65 m氦氧饱和潜水人员生理功能的影响 |
| 文献子类 | Article |
| 英文摘要 | Objective To investigate the effects of piracetam per os on the physiological functions of divers during the simulated 65 m heliox saturation dive. Methods A double-blind experiment was conducted by 7 healthy male divers,who were randomly divided into two groups: the experimental group (n = 3) and the control group (n =4). The subjects in the experimental group began to take piracetam (2.4 g/d) 3 days before entrance into the chamber until one week after they came out of the chamber. The 4 subjects in the control group received excipient at the same time and at the same dose. Changes in respiratory frequency, pulse, blood pressure,24-h urine output and hepatic and renal functions of the divers were observed closely. Results No obvious changes could be noted in respiratory frequency, pulse and 24-h urine output in the two groups. As compared with that before pressure exposure,the diastolic pressure of the divers in the control group increased (P <0. 05),while the diastolic pressure of the divers in the experimental group was lower than that of the control group at the same time points (P <0. 05). The systolic pressure of the divers in the experimental group at the end of decompression was obviously lower than that of the control group (P <0. 05). The concentrations of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the divers of the experimental group after exposure were higher than those before exposure, while the levels of ALT and AST in the control group following exposure were lower than those before exposure, but without statistical significance (P <0. 05). Conclusions Piracetam per os at high pressure seemed to have little adverse effect on divers during the 65 m heliox saturation dive. |
| 资助项目 | 全军后勤科研十一五计划重大项目[00000000] |
| WOS研究方向 | General & Internal Medicine (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:5137593 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/269337]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | Naval Medical Research Institute, Shanghai 200433, China. |
| 推荐引用方式 GB/T 7714 | Li Ci,Fang Yiqun,He Jia,et al. Effect of piracetam per os on physiological functions of divers during the simulated 65 m heliox saturation dive[J]. Chinese Journal of Nautical Medicine and Hyperbaric Medicine,2014,21(2):76-79. |
| APA | Li Ci.,Fang Yiqun.,He Jia.,Liu Yuming.,Chen Ruiyong.,...&Xiao Weibing.(2014).Effect of piracetam per os on physiological functions of divers during the simulated 65 m heliox saturation dive.Chinese Journal of Nautical Medicine and Hyperbaric Medicine,21(2),76-79. |
| MLA | Li Ci,et al."Effect of piracetam per os on physiological functions of divers during the simulated 65 m heliox saturation dive".Chinese Journal of Nautical Medicine and Hyperbaric Medicine 21.2(2014):76-79. |
入库方式： OAI收割
来源：上海药物研究所
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