Synthesis, characterization and cytotoxicity of Diam(m)ineplatinum(II) complexes containing beta-phenylisosuccinate ligand
文献类型：期刊论文
| 作者 | Ye, Qing-Song; Lou, Li-Guang ; Liu, Zuo-Yan; Liu, Wei-Ping; Hou, Shu-Qian; Chen, Xi-Zhu; Yu, Yao
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| 刊名 | ARCHIV DER PHARMAZIE
 |
| 出版日期 | 2007-11 |
| 卷号 | 340期号:11页码:599-602 |
| 关键词 | antitumor activity beta-phenylisosuccinate platinum(II) complex |
| ISSN号 | 0365-6233 |
| DOI | 10.1002/ardp.200700114 |
| 文献子类 | Article |
| 英文摘要 | Four diam(m)ineplatinum(II) complexes containing beta-phenylisosuccinate as the leaving groups were prepared, characterized, and evaluated for their cytotoxicity against A549/ATCC human lung cancer cell line and SGC-7901 human gastric cancer cell line. One of the complexes, (trans1R,2R-diaminocyclohexane)-beta-phenylisosuccinatoplatinum(II) 4, was much more active than cisplatin and carboplatin. |
| WOS关键词 | PLATINUM COMPLEXES ; CRYSTAL-STRUCTURE ; ANTITUMOR-ACTIVITY ; DESIGN STRATEGIES ; PT(II) COMPLEXES ; OXALIPLATIN ; DRUGS ; PERSPECTIVES ; TOXICITY ; ANALOGS |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000251202400005 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273117]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Liu, Wei-Ping |
| 作者单位 | 1.Kunming Inst Precious Metals, Platinum Based Drug Lab, Yunnan 650021, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ye, Qing-Song,Lou, Li-Guang,Liu, Zuo-Yan,et al. Synthesis, characterization and cytotoxicity of Diam(m)ineplatinum(II) complexes containing beta-phenylisosuccinate ligand[J]. ARCHIV DER PHARMAZIE,2007,340(11):599-602. |
| APA | Ye, Qing-Song.,Lou, Li-Guang.,Liu, Zuo-Yan.,Liu, Wei-Ping.,Hou, Shu-Qian.,...&Yu, Yao.(2007).Synthesis, characterization and cytotoxicity of Diam(m)ineplatinum(II) complexes containing beta-phenylisosuccinate ligand.ARCHIV DER PHARMAZIE,340(11),599-602. |
| MLA | Ye, Qing-Song,et al."Synthesis, characterization and cytotoxicity of Diam(m)ineplatinum(II) complexes containing beta-phenylisosuccinate ligand".ARCHIV DER PHARMAZIE 340.11(2007):599-602. |
入库方式： OAI收割
来源：上海药物研究所
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