17-dehydroxyholothurin A, a new sulfated triterpene glycoside from sea cucumber Holothuria impatiens
文献类型：期刊论文
| 作者 | Sun, Peng; Yi, Yang Hua; Li, Ling; Gu, Min ; Tang, Hai Feng; Zhang, Da Zhi; Zhang, Shi Long
|
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2006-11 |
| 卷号 | 17期号:11页码:1454-1456 |
| 关键词 | sea cucumber Holothuria impatiens 17-dehydroxyholothurin A triterpene glycoside |
| ISSN号 | 1001-8417 |
| 文献子类 | Article |
| 英文摘要 | A new sulfated triterpene glycoside named as 17-dehydroxyholothurin A 1 was isolated from the sea cucumber Holothuria impatiens. Its structure was elucidated on the basis of spectroscopic data (2D NMR and MS) and chemical evidence. Compound 1 showed cytotoxic activity against cancer cell lines MKN-28, MFC-7, KB, HL-60 and Hep G2 with IC50 values of 1.98, 4.53, 2.01, 4.69 and 2.80 X 10(-6) mol/L, respectively. |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000243961100010 |
| 出版者 | ELSEVIER SCIENCE INC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273455]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Yi, Yang Hua |
| 作者单位 | 1.Second Mil Med Univ, Sch Pharm, Res Ctr Marine Drug, Shanghai 200433, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Div Antitumor Pharmacol,State Key La Drug Res, Shanghai 201203, Peoples R China 3.Second Mil Med Univ, Sch Pharm, Dept Organ Chem, Shanghai 200433, Peoples R China 4.Fourth Mil Med Univ, Xijing Hosp, Dept Pharm, Xian 710032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Peng,Yi, Yang Hua,Li, Ling,et al. 17-dehydroxyholothurin A, a new sulfated triterpene glycoside from sea cucumber Holothuria impatiens[J]. CHINESE CHEMICAL LETTERS,2006,17(11):1454-1456. |
| APA | Sun, Peng.,Yi, Yang Hua.,Li, Ling.,Gu, Min.,Tang, Hai Feng.,...&Zhang, Shi Long.(2006).17-dehydroxyholothurin A, a new sulfated triterpene glycoside from sea cucumber Holothuria impatiens.CHINESE CHEMICAL LETTERS,17(11),1454-1456. |
| MLA | Sun, Peng,et al."17-dehydroxyholothurin A, a new sulfated triterpene glycoside from sea cucumber Holothuria impatiens".CHINESE CHEMICAL LETTERS 17.11(2006):1454-1456. |
入库方式： OAI收割
来源：上海药物研究所
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