Taraxasterane- and ursane-type triterpenes from Nerium oleander and their biological activities
文献类型：期刊论文
| 作者 | Zhao, Ming; Zhang, Shujun; Fu, Liwei; Li, Na; Bai, Jiao; Sakai, Junichi; Wang, Liyan; Tang, Wanxia; Hasegawa, Toshiaki; Ogura, Hirotsugu |
| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2006-08-25 |
| 卷号 | 69期号:8页码:1164-1167 |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/np0680073 |
| 文献子类 | Article |
| 英文摘要 | Two new taraxasterane-type triterpenes, 20 beta,28-epoxy-28R-methoxytaraxasteran-3 beta-ol (1) and 20 beta,28 alpha-epoxytaraxaster-21-en-3 beta-ol ( 2), were isolated from an ethyl acetate extract of the leaves of Nerium oleander, together with ursane-type triterpenes, 28-nor-urs-12-ene-3 beta, 17 beta-diol (3) and 3 beta-hydroxyurs- 12-en-28-aldehyde (4). The structures of 1 and 2 were established on the basis of their spectroscopic data. Anti-inflammatory activity of 1-4 was examined on the basis of inhibitory activity against the induction of intercellular adhesion molecule-1 (ICAM-1). Cytotoxic activity of 1-4 was evaluated against four human cell lines, A-549, WI-38, VA-13, and HepG2 cells. |
| WOS关键词 | SIGNALING PATHWAY ; ACID |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000240020000009 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273517]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Ando, Masayoshi |
| 作者单位 | 1.Hokkaido Univ, Ctr Instrumental Anal, Kita Ku, Sapporo, Hokkaido 0600812, Japan 2.Niigata Univ, Grad Sch Sci & Technol, Niigata 9502181, Japan 3.Niigata Univ, Dept Chem & Chem Engn, Niigata 9502181, Japan 4.Mitsubishi Gas Chem Co Inc, Niigata Res Lab, Niigata 9503112, Japan 5.Tokyo Inst Technol, Ctr Biol Resources & Informat, Midori Ku, Yokohama, Kanagawa 2268501, Japan 6.Kobe Nat Prod & Chem Co Ltd, Kanzakigun, Hyogo 6792315, Japan 7.Qiqihar Univ, Coll Chem & Chem Engn, Dept Pharm Engn, Qiqihar 161006, Heilongjian, Peoples R China 8.Chinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Ming,Zhang, Shujun,Fu, Liwei,et al. Taraxasterane- and ursane-type triterpenes from Nerium oleander and their biological activities[J]. JOURNAL OF NATURAL PRODUCTS,2006,69(8):1164-1167. |
| APA | Zhao, Ming.,Zhang, Shujun.,Fu, Liwei.,Li, Na.,Bai, Jiao.,...&Ando, Masayoshi.(2006).Taraxasterane- and ursane-type triterpenes from Nerium oleander and their biological activities.JOURNAL OF NATURAL PRODUCTS,69(8),1164-1167. |
| MLA | Zhao, Ming,et al."Taraxasterane- and ursane-type triterpenes from Nerium oleander and their biological activities".JOURNAL OF NATURAL PRODUCTS 69.8(2006):1164-1167. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。