A new rearranged and a new seco-ent-kaurane diterpenoids from Isodon parvifolius
文献类型：期刊论文
| 作者 | Li, Li-Mei; Li, Guo-You; Xiao, Wei-Lie; Zhou, Yan; Li, Sheng-Hong; Huang, Sheng-Xiong; Han, Quan-Bin; Ding, Li-Sheng; Lou, Li-Guang ; Sun, Han-Dong
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| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2006-07-17 |
| 卷号 | 47期号:29页码:5187-5190 |
| ISSN号 | 0040-4039 |
| 关键词 | Isodon parvifolius Labiatae parvifolines X and Y NMR data cytotoxicity |
| DOI | 10.1016/j.tetlet.2006.05.025 |
| 文献子类 | Article |
| 英文摘要 | Parvifoline X (1), a new rearranged ent-kaurane diterpenoid, and parvifoline Y (2), a new 8,15-seco-ent-kaurane diterpenoid, were isolated from the leaves of Isodon parvifolius. Their structures were elucidated by spectroscopic methods including 2D NMR analysis, and supported by a biogenetic pathway. Parvifoline X (1), possessing a new 15(8 -> 11)-abeo-7 alpha,20-epoxy-entkaurane skeleton, was found from the genus Isodon for the first time. Compounds 1 and 2 were evaluated for their inhibitory activity against A549, HT-29, and K562 cell lines. Parvifoline Y (2) was the most cytotoxic against A549 cells with an IC50 value of 4.97 mu M. (c) 2006 Elsevier Ltd. All rights reserved. |
| WOS关键词 | RABDOSIA-PARVIFOLIA ; RUBESCENS ; CRYSTAL |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| WOS记录号 | WOS:000238697600045 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273540]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Sun, Han-Dong |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 200032, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China 4.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Li-Mei,Li, Guo-You,Xiao, Wei-Lie,et al. A new rearranged and a new seco-ent-kaurane diterpenoids from Isodon parvifolius[J]. TETRAHEDRON LETTERS,2006,47(29):5187-5190. |
| APA | Li, Li-Mei.,Li, Guo-You.,Xiao, Wei-Lie.,Zhou, Yan.,Li, Sheng-Hong.,...&Sun, Han-Dong.(2006).A new rearranged and a new seco-ent-kaurane diterpenoids from Isodon parvifolius.TETRAHEDRON LETTERS,47(29),5187-5190. |
| MLA | Li, Li-Mei,et al."A new rearranged and a new seco-ent-kaurane diterpenoids from Isodon parvifolius".TETRAHEDRON LETTERS 47.29(2006):5187-5190. |
入库方式： OAI收割
来源：上海药物研究所
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