A new phenanthrene with a spirolactone from Dendrobium chrysanthum and its anti-inflammatory activities
文献类型：期刊论文
| 作者 | Yang, L; Qin, LH; Bligh, SWA; Bashall, A; Zhang, CF; Zhang, MA; Wang, ZT; Xu, LS |
| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY
 |
| 出版日期 | 2006-05-15 |
| 卷号 | 14期号:10页码:3496-3501 |
| 关键词 | Dendrobium chrysanthum phenanthrene spirolactone anti-inflammatory dendrochrysanene moscatin chrysotoxin |
| ISSN号 | 0968-0896 |
| DOI | 10.1016/j.bmc.2006.01.004 |
| 文献子类 | Article |
| 英文摘要 | Investigation of phenolic patterns from the stems of Dendrobium chrysanthum by HPLC-PDA-MS has led to the isolation of a new phenanthrene derivative with a spirolactone ring, dendrochrysanene (1), that proved to suppress the mRNA level of TNF-alpha, ILS, IL10, and NOS in murine peritoneal macrophages. The structure of 1 was characterized on the basis of various NMR (H-1, C-13, H-1-H-1 COSY, HMQC, and HMBC), mass spectrometry, and X-ray crystal diffraction data. (c) 2006 Elsevier Ltd. All rights reserved. |
| WOS关键词 | DEFICIENT ; ALKALOIDS ; MICE |
| WOS研究方向 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000236952000025 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273595]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Wang, ZT |
| 作者单位 | 1.Hlth Sci Ctr, Joint Imunol Lab, Shanghai 200025, Peoples R China 2.Shanghai Univ Tradit Chinese Med, Shanghai Inst Mat Med, Key Lab Standardizat Chinese Med, Minist Educ, Zhanjiang 201203, Shanghai, Peoples R China 3.China Pharmaceut Univ, Dept Pharmacognosy, Nanjing 210038, Peoples R China 4.Shanghai Med Univ 2, Shanghai 200025, Peoples R China 5.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai 200025, Peoples R China 6.London Metropolitan Univ, Inst Hlth Res & Policy, London N7 8DB, England |
| 推荐引用方式 GB/T 7714 | Yang, L,Qin, LH,Bligh, SWA,et al. A new phenanthrene with a spirolactone from Dendrobium chrysanthum and its anti-inflammatory activities[J]. BIOORGANIC & MEDICINAL CHEMISTRY,2006,14(10):3496-3501. |
| APA | Yang, L.,Qin, LH.,Bligh, SWA.,Bashall, A.,Zhang, CF.,...&Xu, LS.(2006).A new phenanthrene with a spirolactone from Dendrobium chrysanthum and its anti-inflammatory activities.BIOORGANIC & MEDICINAL CHEMISTRY,14(10),3496-3501. |
| MLA | Yang, L,et al."A new phenanthrene with a spirolactone from Dendrobium chrysanthum and its anti-inflammatory activities".BIOORGANIC & MEDICINAL CHEMISTRY 14.10(2006):3496-3501. |
入库方式： OAI收割
来源：上海药物研究所
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