3D-database searching based on the crystal structure of ketol-acid reductoisomerase (KARI) complex
文献类型：期刊论文
| 作者 | Wang, BL; Li, ZM; Ma, Y; Wang, JC; Luo, XM ; Zuo, ZL
|
| 刊名 | CHINESE JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2004-08 |
| 卷号 | 24期号:8页码:973-976 |
| 关键词 | KARI DOCK 3D-database |
| ISSN号 | 0253-2786 |
| 文献子类 | Article |
| 英文摘要 | Based on the reported crystal structure of complexes of the enzyme ketol-acid reductoisomerase (KARI), 279 molecules were obtained with predicted high affinity for KARI from MDL/ACD 3D-database searching, using program DOCK 4.0. The interaction pattern between some top-ranked molecules and KARI was described. These structures provide information for further design of new potential herbicidal molecules targeted at KARI. |
| WOS关键词 | ISOMEROREDUCTASE |
| WOS研究方向 | Chemistry |
| 语种 | 中文 |
| CSCD记录号 | CSCD:1583214 |
| WOS记录号 | WOS:000223147300025 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274041]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Wang, BL |
| 作者单位 | 1.Nankai Univ, Natl Lab Elemento Organ Chem, Inst Elemento Organ Chem, Tianjin 300071, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, BL,Li, ZM,Ma, Y,et al. 3D-database searching based on the crystal structure of ketol-acid reductoisomerase (KARI) complex[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2004,24(8):973-976. |
| APA | Wang, BL,Li, ZM,Ma, Y,Wang, JC,Luo, XM,&Zuo, ZL.(2004).3D-database searching based on the crystal structure of ketol-acid reductoisomerase (KARI) complex.CHINESE JOURNAL OF ORGANIC CHEMISTRY,24(8),973-976. |
| MLA | Wang, BL,et al."3D-database searching based on the crystal structure of ketol-acid reductoisomerase (KARI) complex".CHINESE JOURNAL OF ORGANIC CHEMISTRY 24.8(2004):973-976. |
入库方式： OAI收割
来源：上海药物研究所
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