NMR study on solution configuration of mHCN1 pore peptide
文献类型:期刊论文
| 作者 | Sui, T; Yu, HG; Hu, HY; Shi, YH ; Song, GQ
|
| 刊名 | ACTA BIOCHIMICA ET BIOPHYSICA SINICA
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| 出版日期 | 2003-01 |
| 卷号 | 35期号:1页码:59-63 |
| 关键词 | mHCN1 pore peptide NMR solution structure |
| ISSN号 | 0582-9879 |
| 文献子类 | Article |
| 英文摘要 | Spin systems for amino acid residues in mHCN1 pore region peptide have been identified through analysis of 2D NMR spectra. The sequence-specific assignment of spin systems was obtained by NOEs correlation in WET-NOESY spectra, and the complete assignment of proton resonances for backbone and side chain has been achieved. CNS software was used to calculate the structure of mHCN1 19 aa peptide. The results show that an alpha-helix from residue 10 to residue 13 is formed within the pore region. The results of NMR study on mHCN1 pore peptide provide the basis for further understanding the mechanism of ion selectivity of channels. |
| WOS关键词 | POTASSIUM |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biophysics |
| 语种 | 中文 |
| WOS记录号 | WOS:000180539500010 |
| 出版者 | SHANGHAI INST BIOCHEMISTRY, ACADEMIA SINICA |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274275] ![]() |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, Shanghai 200031, Peoples R China 2.New York Inst Technol, New York Coll Osteopath Med, New York, NY USA 3.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Shanghai 200031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sui, T,Yu, HG,Hu, HY,et al. NMR study on solution configuration of mHCN1 pore peptide[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2003,35(1):59-63. |
| APA | Sui, T,Yu, HG,Hu, HY,Shi, YH,&Song, GQ.(2003).NMR study on solution configuration of mHCN1 pore peptide.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,35(1),59-63. |
| MLA | Sui, T,et al."NMR study on solution configuration of mHCN1 pore peptide".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 35.1(2003):59-63. |
入库方式: OAI收割
来源:上海药物研究所
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