中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
NMR study on solution configuration of mHCN1 pore peptide

文献类型:期刊论文

作者Sui, T; Yu, HG; Hu, HY; Shi, YH; Song, GQ
刊名ACTA BIOCHIMICA ET BIOPHYSICA SINICA
出版日期2003-01
卷号35期号:1页码:59-63
关键词mHCN1 pore peptide NMR solution structure
ISSN号0582-9879
文献子类Article
英文摘要Spin systems for amino acid residues in mHCN1 pore region peptide have been identified through analysis of 2D NMR spectra. The sequence-specific assignment of spin systems was obtained by NOEs correlation in WET-NOESY spectra, and the complete assignment of proton resonances for backbone and side chain has been achieved. CNS software was used to calculate the structure of mHCN1 19 aa peptide. The results show that an alpha-helix from residue 10 to residue 13 is formed within the pore region. The results of NMR study on mHCN1 pore peptide provide the basis for further understanding the mechanism of ion selectivity of channels.
WOS关键词POTASSIUM
WOS研究方向Biochemistry & Molecular Biology ; Biophysics
语种中文
WOS记录号WOS:000180539500010
出版者SHANGHAI INST BIOCHEMISTRY, ACADEMIA SINICA
源URL[http://119.78.100.183/handle/2S10ELR8/274275]  
专题中国科学院上海药物研究所
作者单位1.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, Shanghai 200031, Peoples R China
2.New York Inst Technol, New York Coll Osteopath Med, New York, NY USA
3.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Shanghai 200031, Peoples R China
推荐引用方式
GB/T 7714
Sui, T,Yu, HG,Hu, HY,et al. NMR study on solution configuration of mHCN1 pore peptide[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2003,35(1):59-63.
APA Sui, T,Yu, HG,Hu, HY,Shi, YH,&Song, GQ.(2003).NMR study on solution configuration of mHCN1 pore peptide.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,35(1),59-63.
MLA Sui, T,et al."NMR study on solution configuration of mHCN1 pore peptide".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 35.1(2003):59-63.

入库方式: OAI收割

来源:上海药物研究所

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