Characterization of a rhamnogalacturonan and a xyloglucan from Nerium indicum and their activities on PC12 pheochromocytoma cells
文献类型：期刊论文
| 作者 | Ding, K ; Fang, JN; Dong, TX; Tsim, KWK; Wu, HM
|
| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2003-01 |
| 卷号 | 66期号:1页码:7-10 |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/np020118o |
| 文献子类 | Article |
| 英文摘要 | Two polysaccharides, a rhamnogalacturonan (J1) and a xyloglucan (J2), were isolated and purified from the whole flowers of Nerium indicum and characterized by GC, GC-MS, NMR, and ESMS. The rhamnogalacturonan was found to consist of repeating units of a linear trisaccharide with the structure [-->-4)-alpha-GalpA(1-->2)alpha-Rhap(1-->4)-alpha-GalpA(1-->4)-](n), while the xyloglucan consisted of repeating units of the trisaccharide, which was (1-->4)-linked beta-glucopyranosyl residues as a backbone and substituted at position 6 linked to terminal alpha-xylopyranose side chains. These two polysaccharides were tested on the proliferation and differentiation on PC12 pheochromocytoma cells and found to have effects similar to nerve growth factor (NGF). |
| WOS关键词 | NERVE GROWTH-FACTOR ; HEPARAN-SULFATE PROTEOGLYCANS ; NEURITE OUTGROWTH ; STRUCTURAL CHARACTERIZATION ; POLYSACCHARIDES ; OLIGOSACCHARIDES ; FRAGMENTS ; PROTEIN ; LINE |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000180623400002 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274284]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Fang, JN |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China 3.Hong Kong Univ Sci & Technol, Dept Biol, Hong Kong, Hong Kong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ding, K,Fang, JN,Dong, TX,et al. Characterization of a rhamnogalacturonan and a xyloglucan from Nerium indicum and their activities on PC12 pheochromocytoma cells[J]. JOURNAL OF NATURAL PRODUCTS,2003,66(1):7-10. |
| APA | Ding, K,Fang, JN,Dong, TX,Tsim, KWK,&Wu, HM.(2003).Characterization of a rhamnogalacturonan and a xyloglucan from Nerium indicum and their activities on PC12 pheochromocytoma cells.JOURNAL OF NATURAL PRODUCTS,66(1),7-10. |
| MLA | Ding, K,et al."Characterization of a rhamnogalacturonan and a xyloglucan from Nerium indicum and their activities on PC12 pheochromocytoma cells".JOURNAL OF NATURAL PRODUCTS 66.1(2003):7-10. |
入库方式： OAI收割
来源：上海药物研究所
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