The heterocyclic ring fission and dehydroxylation of catechins and related compounds by Eubacterium sp strain SDG-2, a human intestinal bacterium
文献类型：期刊论文
| 作者 | Wang, LQ; Meselhy, MR; Li, Y ; Nakamura, N; Min, BS; Qin, GW; Hattori, M
|
| 刊名 | CHEMICAL & PHARMACEUTICAL BULLETIN
 |
| 出版日期 | 2001-12 |
| 卷号 | 49期号:12页码:1640-1643 |
| 关键词 | biotransformation heterocyclic ring fission dehydroxylation flavan-3-ol Eubacterium sp strain SDG-2 human intestinal bacterium |
| ISSN号 | 0009-2363 |
| DOI | 10.1248/cpb.49.1640 |
| 文献子类 | Article |
| 英文摘要 | A human intestinal bacterium, Eubacterium (E.) sp. strain SDG-2, was tested for its ability to metabolize various (3R)- and (3S)-flavan-3-ols and their 3-O-gallates. This bacterium cleaved the C-ring of (3R)- and (3S)flavan-3-ols to give 1,3-diphenylpropan-2-ol derivatives, but not their 3-O-gallates. Furthermore, E. sp. strain SDG-2 had the ability of p-dehydroxylation in the B-ring of (3R)-flavan-3-ols, such as (-)-catechin, (-)-epicatechin, (-)-gallocatechin and (-)-epigallocatechin, but not of (3S)-flavan-3-ols, such as (+)-catechin and (+)-epicatechin. |
| WOS关键词 | APOPTOSIS ; CELLS ; INDUCTION |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000172468800024 |
| 出版者 | PHARMACEUTICAL SOC JAPAN |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274422]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Hattori, M |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China 2.Toyama Med & Pharmaceut Univ, Inst Nat Med, Toyama 9300194, Japan |
| 推荐引用方式 GB/T 7714 | Wang, LQ,Meselhy, MR,Li, Y,et al. The heterocyclic ring fission and dehydroxylation of catechins and related compounds by Eubacterium sp strain SDG-2, a human intestinal bacterium[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2001,49(12):1640-1643. |
| APA | Wang, LQ.,Meselhy, MR.,Li, Y.,Nakamura, N.,Min, BS.,...&Hattori, M.(2001).The heterocyclic ring fission and dehydroxylation of catechins and related compounds by Eubacterium sp strain SDG-2, a human intestinal bacterium.CHEMICAL & PHARMACEUTICAL BULLETIN,49(12),1640-1643. |
| MLA | Wang, LQ,et al."The heterocyclic ring fission and dehydroxylation of catechins and related compounds by Eubacterium sp strain SDG-2, a human intestinal bacterium".CHEMICAL & PHARMACEUTICAL BULLETIN 49.12(2001):1640-1643. |
入库方式： OAI收割
来源：上海药物研究所
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