Synthesis of 5-substituted Hexahydro-1H-1,4-diazepine analogues
文献类型：期刊论文
| 作者 | Shen, JS ; Lei, LJ; Mao, HF; Li, JF; Ji, RY
|
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2001-11 |
| 卷号 | 12期号:11页码:951-954 |
| 关键词 | 5-substituted hexahydro-1H-1,4-diazepine analogues synthesis bioactivity |
| ISSN号 | 1001-8417 |
| 文献子类 | Article |
| 英文摘要 | 5-Substituted hexahydro-1H-1,4-diazepine analogues were synthesized starting from N,N'-dibenzyl-1, 2-ethylenediamine and methyl 2, 4-dibromide butyrate through nucleophilic substitution, reduction, chlorination, debenzylation and amidation. Bioactivity tests showed that 9a had the highest agonist activity. |
| WOS关键词 | AGONISTS |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000172123300005 |
| 出版者 | CHINESE CHEMICAL SOCIETY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274434]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China 2.Shanghai Jahwa Fine Chem Co Ltd, Shanghai 200040, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shen, JS,Lei, LJ,Mao, HF,et al. Synthesis of 5-substituted Hexahydro-1H-1,4-diazepine analogues[J]. CHINESE CHEMICAL LETTERS,2001,12(11):951-954. |
| APA | Shen, JS,Lei, LJ,Mao, HF,Li, JF,&Ji, RY.(2001).Synthesis of 5-substituted Hexahydro-1H-1,4-diazepine analogues.CHINESE CHEMICAL LETTERS,12(11),951-954. |
| MLA | Shen, JS,et al."Synthesis of 5-substituted Hexahydro-1H-1,4-diazepine analogues".CHINESE CHEMICAL LETTERS 12.11(2001):951-954. |
入库方式： OAI收割
来源：上海药物研究所
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