Human intestinal bacteria capable of transforming secoisolariciresinol diglucoside to mammalian lignans, enterodiol and enterolactone
文献类型：期刊论文
| 作者 | Wang, LQ; Meselhy, MR; Li, Y ; Qin, GW; Hattori, M
|
| 刊名 | CHEMICAL & PHARMACEUTICAL BULLETIN
 |
| 出版日期 | 2000-11 |
| 卷号 | 48期号:11页码:1606-1610 |
| 关键词 | biotransformation enterodiol enterolactone Eubacterium sp. Peptostreptococcus sp. secoisolariciresinol diglucoside |
| ISSN号 | 0009-2363 |
| 文献子类 | Article |
| 英文摘要 | Seven metabolites were isolated after anaerobic incubation of secoisolariciresinol diglucoside (1) with a human fetal suspension. They were identified as (-)-secoisolariciresinol (2), 3-demethyl-(-)-secoisolariciresinol (3), 2-(3-hydroxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)butane-1,4-diol (4), didemethylsecoisolariciresinol (5), 2-(3-hydroxybenzyl)-3-(3,4-dihydroxybenzyl)butane-1,4-diol (6), enterodiol (7) and enterolactone (8). Furthermore, two bacterial strains, Peptostreptococcus sp. SDG-1 and Eubacterium sp. SDG-2, responsible for the transformation of 1 to a mammalian lignan 7, were isolated from a human fetal suspension. The former transformed 2 to 3 and 5, as well as 4 to 6, and the latter transformed 5 to 6 and 7. |
| WOS关键词 | BREAST-CANCER ; METABOLISM ; EXCRETION ; NUTRITION |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000165110400003 |
| 出版者 | PHARMACEUTICAL SOC JAPAN |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274561]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Hattori, M |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China 2.Toyama Med & Pharmaceut Univ, Inst Nat Med, Toyama 9300194, Japan |
| 推荐引用方式 GB/T 7714 | Wang, LQ,Meselhy, MR,Li, Y,et al. Human intestinal bacteria capable of transforming secoisolariciresinol diglucoside to mammalian lignans, enterodiol and enterolactone[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2000,48(11):1606-1610. |
| APA | Wang, LQ,Meselhy, MR,Li, Y,Qin, GW,&Hattori, M.(2000).Human intestinal bacteria capable of transforming secoisolariciresinol diglucoside to mammalian lignans, enterodiol and enterolactone.CHEMICAL & PHARMACEUTICAL BULLETIN,48(11),1606-1610. |
| MLA | Wang, LQ,et al."Human intestinal bacteria capable of transforming secoisolariciresinol diglucoside to mammalian lignans, enterodiol and enterolactone".CHEMICAL & PHARMACEUTICAL BULLETIN 48.11(2000):1606-1610. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。