Steroidal saponins from the rhizomes of Paris polyphylla var. chinensis and their cytotoxic activity on HL-60 cells
文献类型：期刊论文
| 作者 | Mimaki, Y; Kuroda, M; Obata, Y; Sashida, Y; Kitahara, M; Yasuda, A; Naoi, N; Xu, ZW; Li, MR; Lao, AN |
| 刊名 | NATURAL PRODUCT LETTERS
 |
| 出版日期 | 2000 |
| 卷号 | 14期号:5页码:357-364 |
| 关键词 | Paris polyphylla var. chinensis Liliaceae steroidal saponin spirostanol saponin cytotoxic activity HL-60 cells |
| ISSN号 | 1057-5634 |
| DOI | 10.1080/10575630008043768 |
| 文献子类 | Article |
| 英文摘要 | A new spirostanol steroidal saponin, along with ten known saponins, which were based upon (25R)-spirost-5-en-3 beta-ol (diosgenin) or (25R)-spirost-5-ene-3 beta,17 alpha-diol (pennogenin) as the aglycones, were isolated from the rhizomes of Paris polyphylla var, chinensis. Spectral data, including two-dimensional NMR, and the result of hydrolytic cleavage showed that the structure of the new saponin was pennogenin 3-O-{O-alpha-L-rhamnopyranosyl-(1-->4)-O-alpha-L-rhamnapyranosyl-(1--> 4)-beta-D-glucopyranoside}. The isolated saponins were evaluated for their cytotoxic activity on human promyelocytic leukemia HL-60 cells. |
| WOS关键词 | NMR-SPECTROSCOPY ; GLYCOSIDES ; SAPOGENINS ; SM |
| WOS研究方向 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000089742200006 |
| 出版者 | HARWOOD ACAD PUBL GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274667]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.Kaneka Corp, Med Devices Div, Kita Ku, Osaka 5308288, Japan 2.Acad Sinica, Shanghai Inst Mat Med, Dept Phytochem, Shanghai 200031, Peoples R China 3.Tokyo Univ Pharm & Life Sci, Sch Pharm, Tokyo 1920392, Japan 4.Kaneka Corp, Life Sci RD Ctr, Takasago Res Labs, Takasago, Hyogo 6768688, Japan 5.Tianjin Inst Med & Pharmaceut Sci, Tianjin 300070, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mimaki, Y,Kuroda, M,Obata, Y,et al. Steroidal saponins from the rhizomes of Paris polyphylla var. chinensis and their cytotoxic activity on HL-60 cells[J]. NATURAL PRODUCT LETTERS,2000,14(5):357-364. |
| APA | Mimaki, Y.,Kuroda, M.,Obata, Y.,Sashida, Y.,Kitahara, M.,...&Lao, AN.(2000).Steroidal saponins from the rhizomes of Paris polyphylla var. chinensis and their cytotoxic activity on HL-60 cells.NATURAL PRODUCT LETTERS,14(5),357-364. |
| MLA | Mimaki, Y,et al."Steroidal saponins from the rhizomes of Paris polyphylla var. chinensis and their cytotoxic activity on HL-60 cells".NATURAL PRODUCT LETTERS 14.5(2000):357-364. |
入库方式： OAI收割
来源：上海药物研究所
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