Studies on the antitumor antimony(III) triaminocarboxylic complexonates. Crystal structures of NH4[Sb(Hdtpa)].H2O and Na[Sb(Hdtpa)].4(1/2) H2O (dtpa=diethylenetriaminepentaacetic acid)
文献类型：期刊论文
| 作者 | Hu, SZ; Fu, YM; Xu, B ; Tang, WD; Yu, WJ
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| 刊名 | MAIN GROUP METAL CHEMISTRY
 |
| 出版日期 | 1997-03 |
| 卷号 | 20期号:3页码:169-180 |
| ISSN号 | 0334-7575 |
| 文献子类 | Article |
| 英文摘要 | The structures of NH4[Sb(Hdtpa)]. H2O(1) and Na[Sb(Hdtpa)]. 4 1/2H(2)O(2) were determined by single-crystal X-ray studies. In both complexes, the Ligand dtpa, which is singly protonated, coordinates in a octadentate fashion involving the three nitrogen atoms and five of the carboxylate oxygen atoms of the ligand. The best description appears to be that of a psi-monocapped square antiprism with N(I) being the capping atom and a lone electron pair located on the basal plane of the coordination polyhedron. Bond valence sums were calculated and are given for all Sb(II)-dtpa chelates available to date, and preliminary tests for antitumor activity as well as structure-activity relationships: ate also presented, Crystallographic data: 1, C14H23N4O10Sb . H2O, monoclinic, P2(1)/n, a=6.867(1), b=14. 427(1), c=20.049(1) Angstrom, beta=91.89(1)degrees, Z=4. A total of 3520 reflections was used in the refinement which converged to a final R value of 0.0305; 2, C14H19N3NaO10Sb . 4 1/2 H2O, triclinic, P (1) over bar, a=7.601(1), b=8.576(1), c=17.688(4) Angstrom, a=99. 11(1), beta= 97.01(1), gamma=97.11(1)degrees, Z=2. A total of 3831 reflections was used in the refinement which converged to a final R value of 0.0487. |
| WOS关键词 | POLYHEDRA |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | FREUND PUBLISHING HOUSE |
| WOS记录号 | WOS:A1997WX82700005 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274924]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Hu, SZ |
| 作者单位 | 1.ACAD SINICA,SHANGHAI INST MAT MED,SHANGHAI 200031,PEOPLES R CHINA 2.XIAMEN UNIV,DEPT CHEM,XIAMEN 361005,PEOPLES R CHINA |
| 推荐引用方式 GB/T 7714 | Hu, SZ,Fu, YM,Xu, B,et al. Studies on the antitumor antimony(III) triaminocarboxylic complexonates. Crystal structures of NH4[Sb(Hdtpa)].H2O and Na[Sb(Hdtpa)].4(1/2) H2O (dtpa=diethylenetriaminepentaacetic acid)[J]. MAIN GROUP METAL CHEMISTRY,1997,20(3):169-180. |
| APA | Hu, SZ,Fu, YM,Xu, B,Tang, WD,&Yu, WJ.(1997).Studies on the antitumor antimony(III) triaminocarboxylic complexonates. Crystal structures of NH4[Sb(Hdtpa)].H2O and Na[Sb(Hdtpa)].4(1/2) H2O (dtpa=diethylenetriaminepentaacetic acid).MAIN GROUP METAL CHEMISTRY,20(3),169-180. |
| MLA | Hu, SZ,et al."Studies on the antitumor antimony(III) triaminocarboxylic complexonates. Crystal structures of NH4[Sb(Hdtpa)].H2O and Na[Sb(Hdtpa)].4(1/2) H2O (dtpa=diethylenetriaminepentaacetic acid)".MAIN GROUP METAL CHEMISTRY 20.3(1997):169-180. |
入库方式： OAI收割
来源：上海药物研究所
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