Comparative studies on the mechanism of uridine phosphorolysis
文献类型：期刊论文
| 作者 | Zhao, SR; Chen, KX ; Jiang, HL; Wang, QM; Ji, RY
|
| 刊名 | CHINESE JOURNAL OF CHEMISTRY
 |
| 出版日期 | 1997 |
| 卷号 | 15期号:1页码:84-89 |
| 关键词 | transition state uridine phosphorolysis reaction mechanism nucleophilic substitution intrinsic reaction coordinate |
| ISSN号 | 1001-604X |
| 文献子类 | Article |
| 英文摘要 | We have used quantum mechanical method to study the transition states(TSs) of uridine phosphorolysis reaction. Comparing the four different reaction pathways and the five transition states obtained, we conclude that enzymatic uridine phosphorolysis takes place mainly according to acid-catalyzed S(N)2 mechanism. The proposed reaction pathway is consistent with many experimental results. |
| WOS关键词 | PHOSPHORYLASE |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:A1997XL35400014 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274940]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Zhao, SR |
| 作者单位 | CHINESE ACAD SCI,SHANGHAI INST MAT MED,SHANGHAI 200031,PEOPLES R CHINA. |
| 推荐引用方式 GB/T 7714 | Zhao, SR,Chen, KX,Jiang, HL,et al. Comparative studies on the mechanism of uridine phosphorolysis[J]. CHINESE JOURNAL OF CHEMISTRY,1997,15(1):84-89. |
| APA | Zhao, SR,Chen, KX,Jiang, HL,Wang, QM,&Ji, RY.(1997).Comparative studies on the mechanism of uridine phosphorolysis.CHINESE JOURNAL OF CHEMISTRY,15(1),84-89. |
| MLA | Zhao, SR,et al."Comparative studies on the mechanism of uridine phosphorolysis".CHINESE JOURNAL OF CHEMISTRY 15.1(1997):84-89. |
入库方式： OAI收割
来源：上海药物研究所
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