Ferrous ion induced cleavage of the peroxy bond in qinghaosu and its derivatives and the DNA damage associated with this process
文献类型：期刊论文
| 作者 | Wu, WM; Yao, ZJ; Wu, YL; Kun, JA; Wang, YF; Chen, HB; Shan, F; Li, Y
|
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 1996-09-21 |
| 期号 | 18页码:2213-2214 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/cc9960002213 |
| 文献子类 | Article |
| 英文摘要 | In the presence of iron(II) the peroxy bridge of the drug qinghaosu and its derivatives are cleaved to give two major rearrangement products; DNA damage due to this free radical process is observed and may be responsible for the antimalarial activity of these compounds. |
| WOS关键词 | DECOMPOSITION ; ARTEMISININ |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:A1996VJ63500052 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274958]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 1.CHINESE ACAD SCI,SHANGHAI INST MAT MED,SHANGHAI 200031,PEOPLES R CHINA 2.CHINESE ACAD SCI,SHANGHAI INST ORGAN CHEM,STATE KEY LAB BIOORGAN & NAT PROD CHEM,SHANGHAI 200032,PEOPLES R CHINA |
| 推荐引用方式 GB/T 7714 | Wu, WM,Yao, ZJ,Wu, YL,et al. Ferrous ion induced cleavage of the peroxy bond in qinghaosu and its derivatives and the DNA damage associated with this process[J]. CHEMICAL COMMUNICATIONS,1996(18):2213-2214. |
| APA | Wu, WM.,Yao, ZJ.,Wu, YL.,Kun, JA.,Wang, YF.,...&Li, Y.(1996).Ferrous ion induced cleavage of the peroxy bond in qinghaosu and its derivatives and the DNA damage associated with this process.CHEMICAL COMMUNICATIONS(18),2213-2214. |
| MLA | Wu, WM,et al."Ferrous ion induced cleavage of the peroxy bond in qinghaosu and its derivatives and the DNA damage associated with this process".CHEMICAL COMMUNICATIONS .18(1996):2213-2214. |
入库方式： OAI收割
来源：上海药物研究所
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