COMPARATIVE-STUDY ON INTERMITTENT VERSUS CONTINUOUS USE OF A CONTRACEPTIVE PILL ADMINISTERED BY VAGINAL ROUTE
文献类型：期刊论文
| 作者 | COUTINHO, EM; ODWYER, E; BARBOSA, IC; ZHIPING, G; SHAABAN, MM; ABOULOYOON, M; ALEEM, HA |
| 刊名 | CONTRACEPTION
 |
| 出版日期 | 1995-06 |
| 卷号 | 51期号:6页码:355-358 |
| 关键词 | CONTRACEPTIVE VAGINAL PILL CONTINUOUS VS INTERMITTENT USE |
| ISSN号 | 0010-7824 |
| DOI | 10.1016/0010-7824(95)00101-F |
| 文献子类 | Article |
| 英文摘要 | A multicenter, international, randomized, comparative trial was conducted to assess the acceptability, efficacy and safety of two different schedules of a contraceptive pill, containing 250 mu g levonorgestrel and 50 mu g ethinyl estradiol, administered by the vaginal route. One schedule of daily administration for 21 days with a seven-day interruption to allow withdrawal bleeding was compared to daily administration without interruption for bleeding. A total of 900 women were recruited in three countries, Brazil, Egypt and China; 7,090 women-months of vaginal pill use were recorded (3,364 using the pills intermittently and 3, 726 continuously). Four undesired pregnancies occurred, one in Egypt and three in China, ah four in women using the pills intermittently. There was a statistically significant difference (p=0.486) in pregnancy rate between the two groups. There were no other significant differences in discontinuation rates despite marked differences in bleeding patterns, amenorrhea predominating in the continuous use group. Hemoglobin levels increased significantly in the two groups but hematocrit was significantly higher in the continuous use group. |
| WOS研究方向 | Obstetrics & Gynecology |
| 语种 | 英语 |
| WOS记录号 | WOS:A1995RC98900007 |
| 出版者 | BUTTERWORTH-HEINEMANN |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/275046]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | COUTINHO, EM |
| 作者单位 | 1.UNIV ASSIUT,SCH MED,DEPT OBSTET & GYNECOL,ASSIUT,EGYPT 2.SHANGHAI INST MAT MED,SHANGHAI,PEOPLES R CHINA |
| 推荐引用方式 GB/T 7714 | COUTINHO, EM,ODWYER, E,BARBOSA, IC,et al. COMPARATIVE-STUDY ON INTERMITTENT VERSUS CONTINUOUS USE OF A CONTRACEPTIVE PILL ADMINISTERED BY VAGINAL ROUTE[J]. CONTRACEPTION,1995,51(6):355-358. |
| APA | COUTINHO, EM.,ODWYER, E.,BARBOSA, IC.,ZHIPING, G.,SHAABAN, MM.,...&ALEEM, HA.(1995).COMPARATIVE-STUDY ON INTERMITTENT VERSUS CONTINUOUS USE OF A CONTRACEPTIVE PILL ADMINISTERED BY VAGINAL ROUTE.CONTRACEPTION,51(6),355-358. |
| MLA | COUTINHO, EM,et al."COMPARATIVE-STUDY ON INTERMITTENT VERSUS CONTINUOUS USE OF A CONTRACEPTIVE PILL ADMINISTERED BY VAGINAL ROUTE".CONTRACEPTION 51.6(1995):355-358. |
入库方式： OAI收割
来源：上海药物研究所
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