WHOLE-BODY AUTORADIOGRAPHIC LOCALIZATION OF CATECHOLAMIC ACID IN MICE
文献类型：期刊论文
| 作者 | ZHANG, JS; LIANG, YY; YAN, XM |
| 刊名 | ACTA PHARMACOLOGICA SINICA
 |
| 出版日期 | 1994-01 |
| 卷号 | 15期号:1页码:79-80 |
| 关键词 | CATECHOLAMIC ACID TISSUE DISTRIBUTION AUTORADIOGRAPHY |
| ISSN号 | 0253-9756 |
| 文献子类 | Article |
| 英文摘要 | Catecholamic acid [catechol-3, 6-bis-(methyleneimino diacetic acid)] is a chelating agent synthesized in our institute. Whole-body autoradiogragphic study was carried out to determine the distribution of [C-14]catecholamic acid in 5 adult male mice. Each mouse was injected iv 370 kBq. After various times the mice, under ether anesthesia, were immersed in a mixture of dry ice and hexane. Whole-body sections were made at - 20-degrees-C , 20 mum in thickness. Results showed: (1) At 5 min, higher radioactivities appeared in blood, kidneys, gastrointestinal mucosa, bone, skin, and hair; moderate concentrations in liver, lungs, spleen, and salivary glands. (2) During 20 min and 3 h, the radioactivities decreased (gradually) in all tissues except the bone. (3) Intense radioactivity persisted in the bone, while only traces remained in the kidneys and intestinal mucosa throughout the 24 h period of observation. |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 中文 |
| WOS记录号 | WOS:A1994MR12100016 |
| 出版者 | ACTA PHARMACOLOGICA SINICA |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/275110]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | ZHANG, JS |
| 作者单位 | CHINESE ACAD SCI,SHANGHAI INST MATERIA MED,SHANGHAI 200031,PEOPLES R CHINA. |
| 推荐引用方式 GB/T 7714 | ZHANG, JS,LIANG, YY,YAN, XM. WHOLE-BODY AUTORADIOGRAPHIC LOCALIZATION OF CATECHOLAMIC ACID IN MICE[J]. ACTA PHARMACOLOGICA SINICA,1994,15(1):79-80. |
| APA | ZHANG, JS,LIANG, YY,&YAN, XM.(1994).WHOLE-BODY AUTORADIOGRAPHIC LOCALIZATION OF CATECHOLAMIC ACID IN MICE.ACTA PHARMACOLOGICA SINICA,15(1),79-80. |
| MLA | ZHANG, JS,et al."WHOLE-BODY AUTORADIOGRAPHIC LOCALIZATION OF CATECHOLAMIC ACID IN MICE".ACTA PHARMACOLOGICA SINICA 15.1(1994):79-80. |
入库方式： OAI收割
来源：上海药物研究所
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