EFFECTS OF DIMERCAPTOSUCCINIC ACID PER-OS ON COPPER EXCRETION IN RAT
文献类型：期刊论文
| 作者 | YAN, XM; LI, L ; LIANG, YY; TAO, ZQ; XU, XH; CHEN, ZJ; ZHANG, JS
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| 刊名 | ACTA PHARMACOLOGICA SINICA
 |
| 出版日期 | 1993-11 |
| 卷号 | 14页码:S34-S37 |
| 关键词 | DIMERCAPTOSUCCINIC ACID COPPER ENTEROHEPATIC CIRCULATION ATOMIC ABSORPTION SPECTROPHOTOMETRY |
| ISSN号 | 0253-9756 |
| 文献子类 | Article |
| 英文摘要 | After dimercaptosuccinic acid (DMSA) was given intragastrically by gavage (ig) 0, 250, or 500 mg . kg-1 following im CuSO4 30 mg . kg-1 daily X 3 d in rats, the Cu contents of serum increased markedly within 1-12 h. When ig DMSA daily X 3 d, the excretion of Cu in urine per 24 h in the treated group was greatly promoted vs the control (P < 0.01) , that in the 250 or 500 mg . kg-1 group were enhanced 2.4-3.8 and 5.8-7.8 times, respectively. That the excretion of Cu was increased in bile but not in feces suggested the plausible existence an enterohepatic circulation. |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 日语 |
| WOS记录号 | WOS:A1993MH44400011 |
| 出版者 | ACTA PHARMACOLOGICA SINICA |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/275120]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | YAN, XM |
| 作者单位 | CHINESE ACAD SCI,SHANGHAI INST MAT MED,SHANGHAI 200031,PEOPLES R CHINA. |
| 推荐引用方式 GB/T 7714 | YAN, XM,LI, L,LIANG, YY,et al. EFFECTS OF DIMERCAPTOSUCCINIC ACID PER-OS ON COPPER EXCRETION IN RAT[J]. ACTA PHARMACOLOGICA SINICA,1993,14:S34-S37. |
| APA | YAN, XM.,LI, L.,LIANG, YY.,TAO, ZQ.,XU, XH.,...&ZHANG, JS.(1993).EFFECTS OF DIMERCAPTOSUCCINIC ACID PER-OS ON COPPER EXCRETION IN RAT.ACTA PHARMACOLOGICA SINICA,14,S34-S37. |
| MLA | YAN, XM,et al."EFFECTS OF DIMERCAPTOSUCCINIC ACID PER-OS ON COPPER EXCRETION IN RAT".ACTA PHARMACOLOGICA SINICA 14(1993):S34-S37. |
入库方式： OAI收割
来源：上海药物研究所
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