Anticancer Drug Combinations, How Far We can Go Through?
文献类型：期刊论文
| 作者 | Lu, Da-Yong2,3; Chen, En-Hong3; Wu, Hong-Ying1; Lu, Ting-Ren1; Xu, Bin3 ; Ding, Jian3
|
| 刊名 | ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
 |
| 出版日期 | 2017 |
| 卷号 | 17期号:1页码:21-28 |
| 关键词 | Drug combination drug resistance neoplasm metastasis biotherapy cancer stem cell personalized cancer therapy |
| ISSN号 | 1871-5206 |
| DOI | 10.2174/1871520616666160404112028 |
| 文献子类 | Article |
| 英文摘要 | Many clinical cancer therapies are less effective by using one anticancer drug only due to refractory properties of cancer pathogenesis and drug resistance property in advanced cancer patients. A general consensus among clinicians is that anticancer drug cocktail might better control cancer progresses and metastasis than single drug therapeutics in clinical trials. Despite great popularity, the anticancer drug combination dogma has not been established. The complexity of drug combination dogma discovery is more than we can expect now. This article speculates possible routes we can undertake in this matter. The background knowledge of drug combination therapy presently practiced and possible future landscapes and drawbacks of cancer drug combinative therapies are highlighted. |
| WOS关键词 | CANCER STEM-CELLS ; TRADITIONAL CHINESE MEDICINE ; ADVANCED BREAST-CANCER ; IN-VIVO ; BISDIOXOPIPERAZINE COMPOUNDS ; VENOUS THROMBOEMBOLISM ; MULTIPLE-MYELOMA ; TUMOR-METASTASIS ; TOPOISOMERASE-II ; SOLID TUMORS |
| 资助项目 | Shanghai Science and Technology Foundation of High Educations[97A49] |
| WOS研究方向 | Oncology ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000397225500004 |
| 出版者 | BENTHAM SCIENCE PUBL LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/275724]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Lu, Da-Yong |
| 作者单位 | 1.Shanghai Univ, Coll Sci, Shanghai 200444, Peoples R China 2.Shanghai Univ, Sch Life Sci, Shanghai 200444, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Lu, Da-Yong,Chen, En-Hong,Wu, Hong-Ying,et al. Anticancer Drug Combinations, How Far We can Go Through?[J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY,2017,17(1):21-28. |
| APA | Lu, Da-Yong,Chen, En-Hong,Wu, Hong-Ying,Lu, Ting-Ren,Xu, Bin,&Ding, Jian.(2017).Anticancer Drug Combinations, How Far We can Go Through?.ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY,17(1),21-28. |
| MLA | Lu, Da-Yong,et al."Anticancer Drug Combinations, How Far We can Go Through?".ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY 17.1(2017):21-28. |
入库方式： OAI收割
来源：上海药物研究所
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